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SLC22A3 Products

(Organic Cation Transporter 3 (OCT3))
Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. [provided by RefSeq, Jul 2008].

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Featured SLC22A3 Categories

SLC22A3 Antibodies

High quality antibodies with extensive validation data.

SLC22A3 ELISA Kits

Reliable ELISA kits for a wide range of species.

SLC22A3 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SLC22A3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7192428
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF, ICC
Validations
  • (2)
Cat. No. ABIN6258632
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Human, Pig
Application WB, IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN6736661
Quantity 100 μL
Datasheet Datasheet

Recommended SLC22A3 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1158898
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1158899
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1158900
Quantity 96 tests
Datasheet Datasheet

Recommended SLC22A3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1320211
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3110810
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3120025
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our SLC22A3 products

Zapała, Niemczyk, Zapała, Wdowiak, Bojar, Kluz, Szopa, Serefko, Radziszewski, Wróbel: "The Cannabinoid Ligand Arachidonyl-2'-Chloroethylamide (ACEA) Ameliorates Depressive and Overactive Bladder Symptoms in a Corticosterone-Induced Female Wistar Rat Model." in: International journal of molecular sciences, Vol. 24, Issue 4, (2023) (PubMed).

Juszczak, Adamowicz, Zapała, Kluz, Adamczyk, Wdowiak, Bojar, Misiek, Grzybowska, Stangel-Wójcikiewicz, Poleszak, Pokrywczyńska, Drewa, Wróbel: "Potentilla chinensis aqueous extract attenuates cyclophosphamide-induced hemorrhagic cystitis in rat model." in: Scientific reports, Vol. 12, Issue 1, pp. 13076, (2022) (PubMed).

Zapała, Juszczak, Adamczyk, Adamowicz, Ślusarczyk, Kluz, Misiek, Rogowski, Grzybowska, Stangel-Wójcikiewicz, Zaborowski, Poleszak, Radziszewski, Wróbel: "New Kid on the Block: The Efficacy of Phytomedicine Extracts Urox® in Reducing Overactive Bladder Symptoms in Rats." in: Frontiers in molecular biosciences, Vol. 9, pp. 896624, (2022) (PubMed).

Wróbel, Zapała, Kluz, Rogowski, Misiek, Juszczak, Sieńko, Gold, Stangel-Wójcikiewicz, Poleszak, Radziszewski: "The Potential of Asiatic Acid in the Reversion of Cyclophosphamide-Induced Hemorrhagic Cystitis in Rats." in: International journal of molecular sciences, Vol. 22, Issue 11, (2021) (PubMed).

Wróbel, Serefko, Szopa, Poleszak: "Stimulation of atypical cannabinoid receptor GPR55 abolishes the symptoms of detrusor overactivity in spontaneously hypertensive rats." in: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, Vol. 150, pp. 105329, (2020) (PubMed).

Wróbel, Serefko, Szopa, Poleszak: "Asiatic Acid, a Natural Compound that Exerts Beneficial Effects on the Cystometric and Biochemical Parameters in the Retinyl Acetate-Induced Model of Detrusor Overactivity." in: Frontiers in pharmacology, Vol. 11, pp. 574108, (2020) (PubMed).

Wróbel, Serefko, Szopa, Ulrich, Poleszak, Rechberger: "O-1602, an Agonist of Atypical Cannabinoid Receptors GPR55, Reverses the Symptoms of Depression and Detrusor Overactivity in Rats Subjected to Corticosterone Treatment." in: Frontiers in pharmacology, Vol. 11, pp. 1002, (2020) (PubMed).

Wróbel, Szopa, Serefko, Poleszak: "A Novel Alternative in the Treatment of Detrusor Overactivity? In Vivo Activity of O-1602, the Newly Synthesized Agonist of GPR55 and GPR18 Cannabinoid Receptors." in: Molecules (Basel, Switzerland), Vol. 25, Issue 6, (2020) (PubMed).

Yokoo, Masuda, Yonezawa, Terada, Katsura, Inui: "Significance of organic cation transporter 3 (SLC22A3) expression for the cytotoxic effect of oxaliplatin in colorectal cancer." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 36, Issue 11, pp. 2299-306, (2008) (PubMed).

Kitaichi, Fukuda, Nakayama, Aoyama, Ito, Fujimoto, Takagi, Takagi, Hasegawa: "Behavioral changes following antisense oligonucleotide-induced reduction of organic cation transporter-3 in mice." in: Neuroscience letters, Vol. 382, Issue 1-2, pp. 195-200, (2005) (PubMed).

Synonyms and alternative names related to SLC22A3

solute carrier family 22 member 3 (SLC22A3), solute carrier family 22 member 3 (Slc22a3), solute carrier family 22 (organic cation transporter), member 3 (Slc22a3), EMT, EMTH, OCT3, Oct3, Orct3, Slca22a3

Protein level used designations for SLC22A3

  • organic cation transporter 3
  • extraneuronal monoamine extraneuronal monoamine
  • solute carrier family 22 member 3
  • solute carrier family 22 (extraneuronal monoamine transporter), member 3
  • solute carrier family 22, member 3
  • EMT organic cation transporter 3
  • extraneuronal monoamine transporter
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