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SLC19A3 Products

(Solute Carrier Family 19, Member 3 (Slc19a3))

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This gene encodes a ubiquitously expressed transmembrane thiamine transporter that lacks folate transport activity. Mutations in this gene cause biotin-responsive basal ganglia disease (BBGD)\; a recessive disorder manifested in childhood that progresses to chronic encephalopathy, dystonia, quadriparesis, and death if untreated. Patients with BBGD have bilateral necrosis in the head of the caudate nucleus and in the putamen. Administration of high doses of biotin in the early progression of the disorder eliminates pathological symptoms while delayed treatment results in residual paraparesis, mild mental retardation, or dystonia. Administration of thiamine is ineffective in the treatment of this disorder. Experiments have failed to show that this protein can transport biotin. Mutations in this gene also cause a Wernicke's-like encephalopathy.[provided by RefSeq, Jan 2010].

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Featured SLC19A3 Categories

SLC19A3 Antibodies

High quality antibodies with extensive validation data.

SLC19A3 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SLC19A3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application WB
Validations
  • (5)
Cat. No. ABIN2775519
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (2)
Cat. No. ABIN7171984
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN651538
Quantity 400 μL
Datasheet Datasheet

Recommended SLC19A3 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6225767
Quantity 96 tests
Datasheet Datasheet

Recommended SLC19A3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1320167
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3106401
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3128162
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our SLC19A3 products

Ahn, Wu, Lee: "Integrative Analysis Revealing Human Adipose-Specific Genes and Consolidating Obesity Loci." in: Scientific reports, Vol. 9, Issue 1, pp. 3087, (2019) (PubMed).

Schänzer, Döring, Ondrouschek, Goos, Garvalov, Geyer, Acker, Neubauer, Hahn: "Stress-induced upregulation of SLC19A3 is impaired in biotin-thiamine-responsive basal ganglia disease." in: Brain pathology (Zurich, Switzerland), Vol. 24, Issue 3, pp. 270-9, (2014) (PubMed).

Synonyms and alternative names related to SLC19A3

solute carrier family 19 member 3 (SLC19A3), solute carrier family 19 member 3 (Slc19a3), solute carrier family 19 member 3 L homeolog (slc19a3.L), solute carrier family 19 (thiamine transporter), member 3 (slc19a3), thiamine transporter 2 (LOC486151), solute carrier family 19 (thiamine transporter), member 3b (slc19a3b), solute carrier family 19, member 3 (SLC19A3), thiamine transporter 2-like (LOC100230080), solute carrier family 19, member 3 (Slc19a3), A230084E24Rik, AI788884, BBGD, MGC52872, MGC89434, si:dkey-223n17.4, slc19a3, THMD2, THTR2, thtr2, ThTr2

Protein level used designations for SLC19A3

  • solute carrier family 19, member 3
  • thTr-2
  • thiamine transporter 2
  • solute carrier family 19 (sodium/hydrogen exchanger), member 3
  • thiamine transporter 2-like
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