SKIL Products
(SKI-Like Oncogene (SKIL))
Categories
The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Oct 2011].
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Featured SKIL Categories
SKIL Antibodies
High quality antibodies with extensive validation data.
SKIL ELISA Kits
Reliable ELISA kits for a wide range of species.
SKIL Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SKIL Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IHC (p)
Validations
- (12)
Cat. No.
ABIN1491380
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (4)
Cat. No.
ABIN7169773
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF, ICC
Validations
- (3)
Cat. No.
ABIN6258322
Quantity
100 μL
Datasheet
Datasheet
Recommended SKIL ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959501
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6221322
Quantity
96 tests
Datasheet
Datasheet
Recommended SKIL Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125113
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1320081
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1320083
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our SKIL products
: "Transforming growth factor-β/SMAD Target gene SKIL is negatively regulated by the transcriptional cofactor complex SNON-SMAD4." in: The Journal of biological chemistry, Vol. 287, Issue 32, pp. 26764-76, (2012) (PubMed).: "Ski and SnoN: negative regulators of TGF-beta signaling." in: Current opinion in genetics & development, Vol. 14, Issue 1, pp. 65-70, (2004) (PubMed).
: "TGF-beta signaling in tumor suppression and cancer progression." in: Nature genetics, Vol. 29, Issue 2, pp. 117-29, (2001) (PubMed).
: "Transcriptional control by the TGF-beta/Smad signaling system." in: The EMBO journal, Vol. 19, Issue 8, pp. 1745-54, (2000) (PubMed).
: "Unique sequence, ski, in Sloan-Kettering avian retroviruses with properties of a new cell-derived oncogene." in: Journal of virology, Vol. 57, Issue 3, pp. 1065-72, (1986) (PubMed).
Synonyms and alternative names related to SKIL
SKI like proto-oncogene (SKIL), SKI-like proto-oncogene (Skil), ski-like protein (LOC100010058), SKI-like proto-oncogene (skil), SKI like proto-oncogene (skil), SKI-like (Skil), SKI like proto-oncogene (Skil), SKI-like proto-oncogene b (skilb), DKFZp459L122, SKIL, Skir, SNO, Sno, sno, SnoA, SnoI, SnoN, zgc:193698Protein level used designations for SKIL
- ski-like protein
- ski-related oncogene snoN
- ski/sno related
- SKI-like oncogene
- v-ski sarcoma viral oncogene homolog
- Ski-like protein
- ski-like protein-like
- ski-related oncogene
- LOW QUALITY PROTEIN: ski-like protein
- SKI-like oncogene b
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