SIRT4 Products
(Sirtuin 4 (SIRT4))
Categories
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined\; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. [provided by RefSeq, Jul 2008].
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Featured SIRT4 Categories
SIRT4 Antibodies
High quality antibodies with extensive validation data.
SIRT4 ELISA Kits
Reliable ELISA kits for a wide range of species.
SIRT4 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SIRT4 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (7)
Cat. No.
ABIN7435928
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7437602
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
WB, ELISA, IHC (p)
Validations
- (2)
- (4)
Cat. No.
ABIN872709
Quantity
100 μL
Datasheet
Datasheet
Recommended SIRT4 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN6959494
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5593051
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Sandwich ELISA
Validations
Cat. No.
ABIN434857
Quantity
96 tests
Datasheet
Datasheet
Recommended SIRT4 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125108
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1320049
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1320048
Quantity
25 μg
Datasheet
Datasheet
Latest Publications for our SIRT4 products
: "Adherence to the Mediterranean Diet and Circulating Levels of Sirtuin 4 in Obese Patients: A Novel Association." in: Oxidative medicine and cellular longevity, Vol. 2017, pp. 6101254, (2018) (PubMed).: "SIRT2 deacetylase regulates the activity of GSK3 isoforms independent of inhibitory phosphorylation." in: eLife, Vol. 7, (2018) (PubMed).
: "Tenovin-6 inhibits proliferation and survival of diffuse large B-cell lymphoma cells by blocking autophagy." in: Oncotarget, Vol. 8, Issue 9, pp. 14912-14924, (2017) (PubMed).
: "MicroRNA-15b regulates mitochondrial ROS production and the senescence-associated secretory phenotype through sirtuin 4/SIRT4. ..." in: Aging, Vol. 8, Issue 3, pp. 484-505, (2016) (PubMed).
: "Preliminary data on the relationship between circulating levels of Sirtuin 4, anthropometric and metabolic parameters in obese subjects according to growth hormone/insulin-like growth factor-1 status." in: Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society, Vol. 25, Issue 1, pp. 28-33, (2015) (PubMed).
: "Localization of sirtuins (SIRT1-7) in the aged mouse inner ear." in: Acta oto-laryngologica, pp. 1-12, (2015) (PubMed).
: "Reduction of sulfamethoxazole hydroxylamine (SMX-HA) by the mitochondrial amidoxime reducing component (mARC)." in: Chemical research in toxicology, Vol. 27, Issue 10, pp. 1687-95, (2015) (PubMed).
: "Localization of sirtuins in the mouse inner ear." in: Acta oto-laryngologica, Vol. 134, Issue 4, pp. 331-8, (2014) (PubMed).
: "Effects of niacin restriction on sirtuin and PARP responses to photodamage in human skin." in: PLoS ONE, Vol. 7, Issue 7, pp. e42276, (2012) (PubMed).
: "Reduced expression of SIRT1 is associated with diminished glucose-induced insulin secretion in islets from calorie-restricted rats." in: The Journal of nutritional biochemistry, Vol. 22, Issue 6, pp. 554-9, (2011) (PubMed).
Synonyms and alternative names related to SIRT4
sirtuin 4 (SIRT4), sirtuin 4 (sirt4), sirtuin 4 (Sirt4), 4930596O17Rik, im:7139453, SIR2L4, SIRT4Protein level used designations for SIRT4
- sirtuin (silent mating type information regulation 2 homolog) 4 (S. cerevisiae)
- sirtuin 4
- NAD-dependent ADP-ribosyltransferase sirtuin-4
- NAD-dependent protein deacetylase sirtuin-4
- SIR2-like protein 4
- regulatory protein SIR2 homolog 4
- sir2-like 4
- sirtuin type 4
- NAD-dependent deacetylase sirtuin-4
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