SIRT3 Products
(Sirtuin 3 (SIRT3))
Categories
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined\; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene. [provided by RefSeq, Jul 2008].
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Featured SIRT3 Categories
SIRT3 Antibodies
High quality antibodies with extensive validation data.
SIRT3 ELISA Kits
Reliable ELISA kits for a wide range of species.
SIRT3 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SIRT3 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p)
Validations
- (11)
- (5)
Cat. No.
ABIN390178
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP
Validations
- (1)
- (6)
Cat. No.
ABIN6147792
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p)
Validations
- (2)
- (5)
Cat. No.
ABIN652184
Quantity
200 μL
Datasheet
Datasheet
Recommended SIRT3 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970232
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959491
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959492
Quantity
96 tests
Datasheet
Datasheet
Recommended SIRT3 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1320045
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125107
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1320046
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our SIRT3 products
: "Effects of perinatal factors on sirtuin 3, 8-hydroxy-2'- deoxyguanosine, brain-derived neurotrophic factor and serotonin in cord blood and early breast milk: an observational study." in: International breastfeeding journal, Vol. 15, Issue 1, pp. 57, (2020) (PubMed).: "SirT3 regulates diabetogenic effects caused by arsenic: An implication for mitochondrial complex II modification." in: Toxicology letters, Vol. 301, pp. 24-33, (2019) (PubMed).
: "Single-walled carbon nanohorn aggregates promotes mitochondrial dysfunction-induced apoptosis in hepatoblastoma cells by targeting SIRT3." in: International journal of oncology, Vol. 53, Issue 3, pp. 1129-1137, (2018) (PubMed).
: "Decreased Sirtuin Deacetylase Activity in LRRK2 G2019S iPSC-Derived Dopaminergic Neurons." in: Stem cell reports, Vol. 9, Issue 6, pp. 1839-1852, (2018) (PubMed).
: "SIRT1/3 Activation by Resveratrol Attenuates Acute Kidney Injury in a Septic Rat Model." in: Oxidative medicine and cellular longevity, Vol. 2016, pp. 7296092, (2017) (PubMed).
: "Dysfunctional MnSOD leads to redox dysregulation and activation of prosurvival AKT signaling in uterine leiomyomas." in: Science advances, Vol. 2, Issue 11, pp. e1601132, (2016) (PubMed).
: "Mouse SIRT3 attenuates hypertrophy-related lipid accumulation in the heart through the deacetylation of LCAD." in: PLoS ONE, Vol. 10, Issue 3, pp. e0118909, (2015) (PubMed).
: "Localization of sirtuins (SIRT1-7) in the aged mouse inner ear." in: Acta oto-laryngologica, pp. 1-12, (2015) (PubMed).
: "Oroxylin A inhibits glycolysis-dependent proliferation of human breast cancer via promoting SIRT3-mediated SOD2 transcription and HIF1α destabilization." in: Cell death & disease, Vol. 6, pp. e1714, (2015) (PubMed).
: "Mitochondrial complex II is a source of the reserve respiratory capacity that is regulated by metabolic sensors and promotes cell survival." in: Cell death & disease, Vol. 6, pp. e1835, (2015) (PubMed).
Synonyms and alternative names related to SIRT3
sirtuin 3 (sirt3), sirtuin 3 (SIRT3), sirtuin 3 (Sirt3), 2310003L23Rik, AI848213, SIR2L3, Sir2l3, sirtuin, zgc:158774Protein level used designations for SIRT3
- sirtuin 3
- sirtuin
- NAD-dependent deacetylase sirtuin-3, mitochondrial
- NAD-dependent protein deacetylase sirtuin-3, mitochondrial
- SIR2-like protein 3
- mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase
- regulatory protein SIR2 homolog 3
- silent mating type information regulation 2, S.cerevisiae, homolog 3
- sir2-like 3
- sirtuin type 3
- SIRT3 mitochondrial
- NAD-dependent deacetylase sirtuin-3
- NAD-dependent protein deacetylase sirtuin-3
- SIRT3L mitochondrial
- mSIR2L3
- mitochondrial protein lysine deacetylase
- silent mating type information regulation 2, (S.cerevisiae, homolog)-like 3
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