SIRT2 Products
(Sirtuin 2 (SIRT2))
Categories
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined\; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Several transcript variants are resulted from alternative splicing of this gene. [provided by RefSeq, Jul 2010].
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Featured SIRT2 Categories
SIRT2 Antibodies
High quality antibodies with extensive validation data.
SIRT2 ELISA Kits
Reliable ELISA kits for a wide range of species.
SIRT2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SIRT2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (6)
Cat. No.
ABIN3020852
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, RNAi
Validations
- (5)
Cat. No.
ABIN564966
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p)
Validations
- (6)
Cat. No.
ABIN3043924
Quantity
100 μg
Datasheet
Datasheet
Recommended SIRT2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6959488
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6959490
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959489
Quantity
96 tests
Datasheet
Datasheet
Recommended SIRT2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125105
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1320041
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN6386645
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our SIRT2 products
: "Identification of serum protein biomarkers for utrophin based DMD therapy." in: Scientific reports, Vol. 7, pp. 43697, (2018) (PubMed).: "The effects of melatonin and curcumin on the expression of SIRT2, Bcl-2 and Bax in the hippocampus of adult rats." in: Brain research bulletin, Vol. 137, pp. 306-310, (2018) (PubMed).
: "The subcellular localization and activity of cortactin is regulated by acetylation and interaction with Keap1." in: Science signaling, Vol. 8, Issue 404, pp. ra120, (2016) (PubMed).
: "Acetylation of Beclin 1 inhibits autophagosome maturation and promotes tumour growth." in: Nature communications, Vol. 6, pp. 7215, (2015) (PubMed).
: "A chromatin modifier genetic screen identifies SIRT2 as a modulator of response to targeted therapies through the regulation of MEK kinase activity." in: Oncogene, Vol. 34, Issue 4, pp. 531-6, (2015) (PubMed).
: "NOTCH-induced aldehyde dehydrogenase 1A1 deacetylation promotes breast cancer stem cells." in: The Journal of clinical investigation, (2014) (PubMed).
: "Effects of niacin restriction on sirtuin and PARP responses to photodamage in human skin." in: PLoS ONE, Vol. 7, Issue 7, pp. e42276, (2012) (PubMed).
: "Alcohol-induced alterations in hepatic microtubule dynamics can be explained by impaired histone deacetylase 6 function." in: Hepatology (Baltimore, Md.), Vol. 48, Issue 5, pp. 1671-9, (2008) (PubMed).
: "Osthole regulates enzyme protein expression of CYP7A1 and DGAT2 via activation of PPARalpha/gamma in fat milk-induced fatty liver rats." in: Journal of Asian natural products research, Vol. 10, Issue 7-8, pp. 807-12, (2008) (PubMed).
: "The regulation of SIRT2 function by cyclin-dependent kinases affects cell motility." in: The Journal of cell biology, Vol. 180, Issue 5, pp. 915-29, (2008) (PubMed).
Synonyms and alternative names related to SIRT2
Sirtuin 2 (Sirt2), sirtuin 2 (SIRT2), sirtuin 2 S homeolog (sirt2.S), NAD-dependent deacetylase sirtuin 2 homolog (Sirt2), sirtuin 2 (SRT2), sirtuin 2 (sirt2), sirtuin 2 (Sirt2), sirtuin 2 (silent mating type information regulation 2, homolog) 2 (S. cerevisiae) (sirt2), 5730427M03Rik, AtSRT2, BmSirt2, CG5085, D.mel2, Dmel\\CG5085, dSIRT2, sir2, SIR2, SIR2L, Sir2l, SIR2L2, SIRT2, Sirt2, SIRTUIN 2, sirtuin 2, T2K12.8, wu:fb57d05, zgc:55966, zgc:77003Protein level used designations for SIRT2
- CG5085-PA
- Sirt2-PA
- sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae)
- sirtuin 2
- NAD-dependent deacetylase SIRT2
- NAD-dependent deacetylase sirtuin-2
- histone NADC
- silent information regulator 2
- nicotinamide adenine dinucleotide-dependent histone deacetylase
- NAD-dependent deacetylase sirtuin 2 homolog
- NAD-dependent protein deacetylase sirtuin-2
- SIR2-like protein 2
- regulatory protein SIR2 homolog 2
- sir2-related protein type 2
- sirtuin type 2
- sirtuin-like protein 2
- mSIR2L2
- silent mating type information regulation 2, (S.cerevisiae, homolog)-like; sirtuin 2
- 5E5 antigen
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