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SIRT1 Antibodies

(Sirtuin 1 (SIRT1))

SIRT1 (Sirtuin 1) is a protein that plays a role in regulating metabolism and has been implicated in the development and progression of obesity. Several studies have investigated the potential of targeting SIRT1 as a therapeutic strategy for obesity.

Research has shown that SIRT1 is involved in the regulation of nutrient sensing and can modulate lipid and glucose metabolism. It has been found to protect against high-fat diet-induced metabolic damage and hepatic lipid accumulation. SIRT1 has also been shown to promote lipid metabolism and mitochondrial function, which are important processes in adipogenesis and obesity.

In addition, SIRT1 has been found to counteract aging- and obesity-related diseases by deacetylating many proteins. It has been suggested that targeting SIRT1 activity in the brain may show promise for the treatment of obesity and associated metabolic disorders.

SIRT1 antibodies are essential research tools for better understanding the role of SIRT1 in in regulating metabolism, lipid metabolism, and mitochondrial function.

SIRT1 antibody  (AA 101-200) SIRT1 antibody  (AA 101-200) SIRT1 antibody (AA 101-200) (ABIN729853)

SIRT1 Reactivity: Human, Mouse, Rat WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated

SIRT1 antibody  (AA 456-555) SIRT1 antibody  (AA 456-555) SIRT1 antibody (AA 456-555) (ABIN565071)

SIRT1 Reactivity: Human WB, ELISA, IF, IHC (p) Host: Mouse Monoclonal 7B7 unconjugated

SIRT1 antibody  (AA 448-747) SIRT1 antibody  (AA 448-747) SIRT1 antibody (AA 448-747) (ABIN6147784)

SIRT1 Reactivity: Human WB, IHC, IP, IF Host: Rabbit Polyclonal unconjugated

SIRT1 Antibodies by Grade

Find SIRT1 Antibodies with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

SIRT1 Antibodies by Reactivity

Find SIRT1 Antibodies for a variety of species such as anti-Human SIRT1, anti-Mouse SIRT1, anti-Rat SIRT1. The species listed below are among those available. Click on a link to go to the corresponding products.

SIRT1 Antibodies by Application

Find SIRT1 Antibodies validated for a specific application such as WB, FACS, ELISA, IF (cc). Some of the available applications are listed below. Click on a link to go to the corresponding products.

SIRT1 Antibodies by Host

Find SIRT1 Antibodies with a specific Host. The Host listed below are among those available. Click on a link to go to the corresponding products.

SIRT1 Antibodies by Binding Specificity

Find SIRT1 Antibodies with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

SIRT1 Antibodies by Clonality

Find available monoclonal or polyclonal SIRT1 Antibodies. Click on a link to go to the corresponding products.

SIRT1 Antibodies by Clone

Find SIRT1 Antibodies with a specific Clone. The Clone listed below are among those available. Click on a link to go to the corresponding products.

SIRT1 Antibodies by Conjugate

Find SIRT1 Antibodies with a specific conjugate such as Biotin, FITC, Alexa Fluor 488. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular SIRT1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (5)
  • (7)
Cat. No. ABIN729853
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC (p)
Validations
  • (3)
  • (5)
Cat. No. ABIN565071
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, IF
Validations
  • (9)
Cat. No. ABIN6147784
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IF, IHC (p)
Validations
  • (1)
  • (4)
Cat. No. ABIN6242824
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, FACS, ICC
Validations
  • (2)
  • (4)
Cat. No. ABIN969396
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, IF, ChIP
Validations
  • (4)
Cat. No. ABIN7270322
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB
Validations
  • (5)
  • (4)
Cat. No. ABIN2779607
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC, IF
Validations
  • (5)
Cat. No. ABIN3032583
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p), EIA
Validations
  • (5)
Cat. No. ABIN614713
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7435913
Quantity 100 μL
Datasheet Datasheet
Reactivity Dog, Human, Mouse, Rat
Application WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (4)
  • (2)
Cat. No. ABIN745658
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB
Validations
  • (2)
  • (2)
Cat. No. ABIN1882053
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (2)
Cat. No. ABIN7160851
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (2)
Cat. No. ABIN7435916
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (2)
Cat. No. ABIN7127809
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our SIRT1 Antibodies

Zbroch, Bazyluk, Malyszko, Koc-Zorawska, Rydzewska-Rosolowska, Kakareko, Hryszko: "The Serum Concentration of Anti-Aging Proteins, Sirtuin1 and αKlotho in Patients with End-Stage Kidney Disease on Maintenance Hemodialysis." in: Clinical interventions in aging, Vol. 15, pp. 387-393, (2020) (PubMed).

Yang, Wang, He, Liu, Chen, Wang, Wang, Wang: "Trimetazidine Inhibits Renal Tubular Epithelial Cells to Mesenchymal Transition in Diabetic Rats via Upregulation of Sirt1." in: Frontiers in pharmacology, Vol. 11, pp. 1136, (2020) (PubMed).

Ascenzi, Barberi, Dobrowolny, Villa Nova Bacurau, Nicoletti, Rizzuto, Rosenthal, Scicchitano, Musarò: "Effects of IGF-1 isoforms on muscle growth and sarcopenia." in: Aging cell, Vol. 18, Issue 3, pp. e12954, (2019) (PubMed).

Takata, Sakasai-Sakai, Takino, Takeuchi: "Evidence for Toxic Advanced Glycation End-Products Generated in the Normal Rat Liver." in: Nutrients, Vol. 11, Issue 7, (2019) (PubMed).

Yanes, Zhang, Shen, Weyand, Goronzy: "Metabolic reprogramming in memory CD4 T cell responses of old adults." in: Clinical immunology (Orlando, Fla.), Vol. 207, pp. 58-67, (2019) (PubMed).

Zhang, Abdukerim, Abilailieti, Tang, Ling, Pan: "The protective effects of orexin a against high glucose-induced activation of NLRP3 inflammasome in human vascular endothelial cells." in: Archives of biochemistry and biophysics, Vol. 672, pp. 108052, (2019) (PubMed).

Piao, Zhao, Zhu, Inoue, Shibata, Lei, Hu, Yu, Yang, Wu, Xu, Okumura, Ouchi, Murohara, Kuzuya, Cheng: "Chronic Psychological Stress Accelerates Vascular Senescence and Impairs Ischemia-Induced Neovascularization: The Role of Dipeptidyl Peptidase-4/Glucagon-Like Peptide-1-Adiponectin Axis." in: Journal of the American Heart Association, Vol. 6, Issue 10, (2018) (PubMed).

Zang, Fan, Chen, Huang, Qin: "Improvement of Lipid and Glucose Metabolism by Capsiate in Palmitic Acid-Treated HepG2 Cells via Activation of the AMPK/SIRT1 Signaling Pathway." in: Journal of agricultural and food chemistry, Vol. 66, Issue 26, pp. 6772-6781, (2018) (PubMed).

Zeng, Hu, He, Wang, Li, Xiong, Ye: "Hypothermic machine perfusion ameliorates inflammation during ischemia‑reperfusion injury via sirtuin‑1‑mediated deacetylation of nuclear factor‑κB p65 in rat livers donated after circulatory death." in: Molecular medicine reports, Vol. 16, Issue 6, pp. 8649-8656, (2018) (PubMed).

Zhang, Zhang, Guo, Zeng, Wu, Liu, He, Wang, Huang, Chen: "Sirt1 Protects Endothelial Cells against LPS-Induced Barrier Dysfunction." in: Oxidative medicine and cellular longevity, Vol. 2017, pp. 4082102, (2018) (PubMed).

Aliases for SIRT1 Antibodies

sirtuin 1 (SIRT1) Antibodies
sirtuin 1 (SRT1) Antibodies
sirtuin 1 (Sirt1) Antibodies
sirtuin 1 L homeolog (sirt1.L) Antibodies
AA673258 Antibodies
Sir2 Antibodies
SIR2 Antibodies
Sir2a Antibodies
Sir2alpha Antibodies
SIR2L1 Antibodies
sir2l1 Antibodies
sirtuin Antibodies
sirtuin 1 Antibodies
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