SIRT1 Products
(Sirtuin 1 (SIRT1))
Categories
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined\; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008].
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Featured SIRT1 Categories
SIRT1 Antibodies
High quality antibodies with extensive validation data.
SIRT1 ELISA Kits
Reliable ELISA kits for a wide range of species.
SIRT1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SIRT1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (5)
- (7)
Cat. No.
ABIN729853
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IHC (p)
Validations
- (3)
- (5)
Cat. No.
ABIN565071
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, IF
Validations
- (9)
Cat. No.
ABIN6147784
Quantity
100 μL
Datasheet
Datasheet
Recommended SIRT1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (8)
- (1)
Cat. No.
ABIN6959485
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (4)
- (1)
Cat. No.
ABIN6959487
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970229
Quantity
96 tests
Datasheet
Datasheet
Recommended SIRT1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125104
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1320039
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN2131842
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our SIRT1 products
: "Shikonin Alleviates Gentamicin-Induced Renal Injury in Rats by Targeting Renal Endocytosis, SIRT1/Nrf2/HO-1, TLR-4/NF-κB/MAPK, and PI3K/Akt Cascades." in: Antibiotics (Basel, Switzerland), Vol. 12, Issue 5, (2023) (PubMed).: "The Serum Concentration of Anti-Aging Proteins, Sirtuin1 and αKlotho in Patients with End-Stage Kidney Disease on Maintenance Hemodialysis." in: Clinical interventions in aging, Vol. 15, pp. 387-393, (2020) (PubMed).
: "Trimetazidine Inhibits Renal Tubular Epithelial Cells to Mesenchymal Transition in Diabetic Rats via Upregulation of Sirt1." in: Frontiers in pharmacology, Vol. 11, pp. 1136, (2020) (PubMed).
: "Effects of IGF-1 isoforms on muscle growth and sarcopenia." in: Aging cell, Vol. 18, Issue 3, pp. e12954, (2019) (PubMed).
: "Evidence for Toxic Advanced Glycation End-Products Generated in the Normal Rat Liver." in: Nutrients, Vol. 11, Issue 7, (2019) (PubMed).
: "Metabolic reprogramming in memory CD4 T cell responses of old adults." in: Clinical immunology (Orlando, Fla.), Vol. 207, pp. 58-67, (2019) (PubMed).
: "The protective effects of orexin a against high glucose-induced activation of NLRP3 inflammasome in human vascular endothelial cells." in: Archives of biochemistry and biophysics, Vol. 672, pp. 108052, (2019) (PubMed).
: "Centella asiatica Prevents Increase of Hippocampal Tumor Necrosis Factor-α Independently of Its Effect on Brain-Derived Neurotrophic Factor in Rat Model of Chronic Stress." in: BioMed research international, Vol. 2019, pp. 2649281, (2019) (PubMed).
: "Association of SIRT1 gene polymorphism and its expression for the risk of alcoholic fatty liver disease in the Han population." in: Hepatology international, Vol. 12, Issue 1, pp. 56-66, (2018) (PubMed).
: "Chronic Psychological Stress Accelerates Vascular Senescence and Impairs Ischemia-Induced Neovascularization: The Role of Dipeptidyl Peptidase-4/Glucagon-Like Peptide-1-Adiponectin Axis." in: Journal of the American Heart Association, Vol. 6, Issue 10, (2018) (PubMed).
Synonyms and alternative names related to SIRT1
sirtuin 1 (SIRT1), sirtuin 1 (SRT1), sirtuin 1 (Sirt1), sirtuin 1 L homeolog (sirt1.L), AA673258, Sir2, SIR2, Sir2a, Sir2alpha, SIR2L1, sir2l1, sirtuin, sirtuin 1Protein level used designations for SIRT1
- sirtuin 1
- NAD-dependent deacetylase sirtuin-1
- NAD-dependent protein deacetylase sirtuin-1
- SIR2-like protein 1
- mSIR2a
- regulatory protein SIR2 homolog 1
- sir2-like 1
- sirtuin 1 ((silent mating type information regulation 2, homolog) 1
- SIR2alpha
- hSIR2
- hSIRT1
- sirtuin type 1
- sirtuin (silent mating type information regulation 2 homolog) 1
- NAD-dependent deacetylase sirtuin 1
- sirtuin1
- Sir2alpha
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