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SIRPB1 Products

(Signal-Regulatory Protein beta 1 (SIRPB1))

Categories

The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009].

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Featured SIRPB1 Categories

SIRPB1 Antibodies

High quality antibodies with extensive validation data.

SIRPB1 ELISA Kits

Reliable ELISA kits for a wide range of species.

SIRPB1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SIRPB1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (4)
Cat. No. ABIN7169707
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7169703
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Rat
Application WB, ELISA, ICC, IF
Validations
  • (3)
Cat. No. ABIN6257995
Quantity 100 μL
Datasheet Datasheet

Recommended SIRPB1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959482
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6730435
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6213376
Quantity 96 tests
Datasheet Datasheet

Recommended SIRPB1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275660
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275661
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1320035
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our SIRPB1 products

Hatherley, Graham, Turner, Harlos, Stuart, Barclay: "Paired receptor specificity explained by structures of signal regulatory proteins alone and complexed with CD47." in: Molecular cell, Vol. 31, Issue 2, pp. 266-77, (2008) (PubMed).

Deloukas, Matthews, Ashurst, Burton, Gilbert, Jones, Stavrides, Almeida, Babbage, Bagguley, Bailey, Barlow, Bates, Beard, Beare, Beasley, Bird, Blakey, Bridgeman, Brown, Buck, Burrill, Butler, Carder et al.: "The DNA sequence and comparative analysis of human chromosome 20. ..." in: Nature, Vol. 414, Issue 6866, pp. 865-71, (2002) (PubMed).

Seiffert, Brossart, Cant, Cella, Colonna, Brugger, Kanz, Ullrich, Bühring: "Signal-regulatory protein alpha (SIRPalpha) but not SIRPbeta is involved in T-cell activation, binds to CD47 with high affinity, and is expressed on immature CD34(+)CD38(-) hematopoietic cells." in: Blood, Vol. 97, Issue 9, pp. 2741-9, (2001) (PubMed).

Synonyms and alternative names related to SIRPB1

signal regulatory protein beta 1 (SIRPB1), signal-regulatory protein beta-1 (LOC458036), signal-regulatory protein beta-1 (LOC458430), signal-regulatory protein beta-1 (LOC485809), signal-regulatory protein beta-1 (LOC715912), signal-regulatory protein beta-1 isoform 3 (LOC100458151), CD172b, SIRP-BETA-1, SIRPB1, SIRPG

Protein level used designations for SIRPB1

  • CD172 antigen-like family member B
  • signal-regulatory protein beta-1
  • signal-regulatory protein beta 1
  • signal-regulatory protein gamma
  • signal-regulatory protein beta-1 isoform 3-like
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