SIM2 Products
(Single-Minded Homolog 2 (SIM2))
Categories
SIM1 and SIM2 genes are Drosophila single-minded (sim) gene homologs. The Drosophila sim gene encodes a transcription factor that is a master regulator of fruit fly neurogenesis. SIM2 maps within the so-called Down syndrome chromosomal region. Based on the mapping position, its potential function as transcriptional repressor and similarity to Drosophila sim, it is proposed that SIM2 may contribute to some specific Down syndrome phenotypes [provided by RefSeq, Jul 2008].
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Featured SIM2 Categories
SIM2 Antibodies
High quality antibodies with extensive validation data.
SIM2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SIM2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, WB
Validations
- (1)
- (2)
Cat. No.
ABIN562879
Quantity
50 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB
Validations
- (2)
Cat. No.
ABIN562880
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application
WB
Validations
- (1)
- (2)
Cat. No.
ABIN2780639
Quantity
100 μL
Datasheet
Datasheet
Recommended SIM2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6234812
Quantity
96 tests
Datasheet
Datasheet
Recommended SIM2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125101
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3077116
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3122841
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our SIM2 products
: "Expression of trisomic proteins in Down syndrome model systems." in: Gene, Vol. 512, Issue 2, pp. 219-25, (2012) (PubMed).: "Celastrol regulates multiple nuclear transcription factors belonging to HSP90's clients in a dose- and cell type-dependent way." in: Cell stress & chaperones, Vol. 15, Issue 6, pp. 939-46, (2010) (PubMed).
: "[Association study of SIM2 gene polymorphisms with susceptibility to congenital scoliosis in a Chinese Han population]." in: Zhonghua yi xue za zhi, Vol. 89, Issue 41, pp. 2888-93, (2010) (PubMed).
Synonyms and alternative names related to SIM2
single-minded family bHLH transcription factor 2 S homeolog (sim2.S), single-minded family bHLH transcription factor 2 (sim2), single-minded family bHLH transcription factor 2 (SIM2), single-minded homolog 2 (Drosophila) (SIM2), single-minded homolog 2 (Drosophila) (Sim2), single-minded family bHLH transcription factor 2 (Sim2), bHLHe15, HMC13F06, HMC29C01, SIM, sim2-A, xSim, Xsim2Protein level used designations for SIM2
- single-minded homolog 2
- class E basic helix-loop-helix protein 15
- single-minded homolog 2, short isoform
- transcription factor SIM2
- single-minded (Drosophila) homolog 2
- SIM transcription factor
- mSIM
- single-minded 2
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