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SIGLEC9 Products

(Sialic Acid Binding Ig-Like Lectin 9 (SIGLEC9))

Categories

Putative adhesion molecule that mediates sialic-acid dependent binding to cells. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules.

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Featured SIGLEC9 Categories

SIGLEC9 Antibodies

High quality antibodies with extensive validation data.

SIGLEC9 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SIGLEC9 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, FACS, ICC, Neut
Validations
  • (4)
Cat. No. ABIN5684127
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, FACS, ICC, IP
Validations
  • (2)
Cat. No. ABIN7505917
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7236544
Quantity 200 μL
Datasheet Datasheet

Recommended SIGLEC9 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN625353
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6385675
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN822729
Quantity 96 tests
Datasheet Datasheet

Recommended SIGLEC9 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275608
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN7275594
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN6964319
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our SIGLEC9 products

Zeng, Li, Wang, Wu, Li, Ning, Zhao, Xu, Xie: "Increased expression of Siglec-9 in chronic obstructive pulmonary disease." in: Scientific reports, Vol. 7, Issue 1, pp. 10116, (2017) (PubMed).

Ishikawa, Takahashi, Matsumoto, Yoshioka, Yamamoto, Nishikawa, Hibi, Ishigro, Ueda, Furukawa, Yamamoto: "Factors secreted from dental pulp stem cells show multifaceted benefits for treating experimental rheumatoid arthritis." in: Bone, Vol. 83, pp. 210-9, (2016) (PubMed).

Madge, Maggioni, Pascolutti, Amin, Waespy, Bellette, Thomson, Kelm, von Itzstein, Haselhorst: "Structural characterisation of high affinity Siglec-2 (CD22) ligands in complex with whole Burkitt's lymphoma (BL) Daudi cells by NMR spectroscopy." in: Scientific reports, Vol. 6, pp. 36012, (2016) (PubMed).

Matsubara, Matsushita, Sakai, Kano, Kondo, Noda, Hashimoto, Imagama, Ishiguro, Suzumura, Ueda, Furukawa, Yamamoto: "Secreted ectodomain of sialic acid-binding Ig-like lectin-9 and monocyte chemoattractant protein-1 promote recovery after rat spinal cord injury by altering macrophage polarity." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 6, pp. 2452-64, (2015) (PubMed).

Béziat, Dalgard, Asselah, Halfon, Bedossa, Boudifa, Hervier, Theodorou, Martinot, Debré, Björkström, Malmberg, Marcellin, Vieillard: "CMV drives clonal expansion of NKG2C+ NK cells expressing self-specific KIRs in chronic hepatitis patients." in: European journal of immunology, Vol. 42, Issue 2, pp. 447-57, (2012) (PubMed).

Laarman, Mijnheer, Mootz, van Rooijen, Ruyken, Malone, Heezius, Ward, Milligan, van Strijp, de Haas, Horswill, van Kessel, Rooijakkers: "Staphylococcus aureus Staphopain A inhibits CXCR2-dependent neutrophil activation and chemotaxis." in: The EMBO journal, Vol. 31, Issue 17, pp. 3607-19, (2012) (PubMed).

Zou, Chastain, Moir, Ford, Trandem, Martinelli, Cicala, Crocker, Arthos, Sun: "Siglecs facilitate HIV-1 infection of macrophages through adhesion with viral sialic acids." in: PLoS ONE, Vol. 6, Issue 9, pp. e24559, (2011) (PubMed).

Llinàs, Lázaro, de Salort, Matesanz-Isabel, Sintes, Engel: "Expression profiles of novel cell surface molecules on B-cell subsets and plasma cells as analyzed by flow cytometry." in: Immunology letters, Vol. 134, Issue 2, pp. 113-21, (2010) (PubMed).

Carlin, Uchiyama, Chang, Lewis, Nizet, Varki: "Molecular mimicry of host sialylated glycans allows a bacterial pathogen to engage neutrophil Siglec-9 and dampen the innate immune response." in: Blood, Vol. 113, Issue 14, pp. 3333-6, (2009) (PubMed).

Ando, Tu, Nishijima, Iijima: "Siglec-9 enhances IL-10 production in macrophages via tyrosine-based motifs." in: Biochemical and biophysical research communications, Vol. 369, Issue 3, pp. 878-83, (2008) (PubMed).

Synonyms and alternative names related to SIGLEC9

sialic acid binding Ig like lectin 9 (SIGLEC9), sialic acid-binding immunoglobulin-like lectin 9 (SIGLEC9), CD329, CDw329, FOAP-9, OBBP-LIKE, siglec-9, siglec9

Protein level used designations for SIGLEC9

  • protein FOAP-9
  • sialic acid-binding Ig-like lectin 9
  • sialic acid-binding immunoglobulin-like lectin 9
  • sialic acid binding Ig-like lectin 9
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