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SIGLEC12 Proteins

(Sialic Acid Binding Ig-Like Lectin 12 (SIGLEC12))

Sialic acid-binding immunoglobulin-like lectins (SIGLECs) are a family of cell surface proteins belonging to the immunoglobulin superfamily. They mediate protein-carbohydrate interactions by selectively binding to different sialic acid moieties present on glycolipids and glycoproteins. This gene encodes a member of the SIGLEC3-like subfamily of SIGLECs. Members of this subfamily are characterized by an extracellular V-set immunoglobulin-like domain followed by two C2-set immunoglobulin-like domains, and the cytoplasmic tyrosine-based motifs ITIM and SLAM-like. The encoded protein, upon tyrosine phosphorylation, has been shown to recruit the Src homology 2 domain-containing protein-tyrosine phosphatases SHP1 and SHP2. It has been suggested that the protein is involved in the negative regulation of macrophage signaling by functioning as an inhibitory receptor. This gene is located in a cluster with other SIGLEC3-like genes on 19q13.4. Alternatively spliced transcript variants encoding distinct isoforms have been described for this gene. [provided by RefSeq, Jul 2008].

recommended

SIGLEC12 Protein (AA 503-595) (GST tag) (ABIN1319989)

SIGLEC12 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

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recommended

SIGLEC12 Protein (AA 153-251) (GST tag) (ABIN1319987)

SIGLEC12 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

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recommended

SIGLEC12 Protein (AA 1-595) (GST tag) (ABIN1319985)

SIGLEC12 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

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SIGLEC12 Proteins by Origin

Find SIGLEC12 Proteins for a variety of species such as anti-Human SIGLEC12, anti-Mouse SIGLEC12, anti-Chimpanzee SIGLEC12. The species listed below are among those available. Click on a link to go to the corresponding products.

SIGLEC12 Proteins by Source

Here you will find SIGLEC12 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

SIGLEC12 Proteins by Protein Type

Here you can find SIGLEC12 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

SIGLEC12 Proteins by Application

Find SIGLEC12 Proteins validated for a specific application such as WB, ELISA, SDS, AP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular SIGLEC12 Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

SIGLEC12 Protein (AA 503-595) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1319989

Quantity 10 μg

Datasheet Datasheet

SIGLEC12 Protein (AA 153-251) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1319987

Quantity 10 μg

Datasheet Datasheet

SIGLEC12 Protein (AA 1-595) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1319985

Quantity 10 μg

Datasheet Datasheet

SIGLEC12 Protein (AA 27-141) (His tag)

Reactivity Mouse

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7400804

Quantity 100 μg

Datasheet Datasheet

SIGLEC12 Protein (AA 317-512) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7404062

Quantity 100 μg

Datasheet Datasheet

SIGLEC12 Protein (AA 22-218) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7403318

Quantity 100 μg

Datasheet Datasheet

SIGLEC12 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2732049

Quantity 20 μg

Datasheet Datasheet

SIGLEC12 Protein

Reactivity Mouse

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN3011643

Quantity 100 μg

Datasheet Datasheet

SIGLEC12 Protein (AA 21-483) (His tag)

Reactivity Chimpanzee

Source Yeast

Validations

Cat. No. ABIN1641406

Quantity 1 mg

Datasheet Datasheet

Aliases for SIGLEC12 Proteins

sialic acid binding Ig like lectin 12 (gene/pseudogene) (SIGLEC12) Proteins
sialic acid binding Ig like lectin 12 (SIGLEC12) Proteins
sialic acid binding Ig-like lectin 12 (SIGLEC12) Proteins
S2V Proteins
Siglec-XII Proteins
SIGLECL1 Proteins
SLG Proteins

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SIGLEC12 Proteins by Origin

SIGLEC12 Proteins by Source

SIGLEC12 Proteins by Protein Type

SIGLEC12 Proteins by Application

Popular SIGLEC12 Proteins

Aliases for SIGLEC12 Proteins

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