SIAH1 Products
(E3 Ubiquitin-Protein Ligase SIAH1 (SIAH1))
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This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq, Jul 2008].
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Featured SIAH1 Categories
SIAH1 Antibodies
High quality antibodies with extensive validation data.
SIAH1 ELISA Kits
Reliable ELISA kits for a wide range of species.
SIAH1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SIAH1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Rat
Application
WB, ELISA, IF
Validations
- (1)
- (8)
Cat. No.
ABIN184675
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (7)
Cat. No.
ABIN3016132
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (3)
Cat. No.
ABIN520188
Quantity
100 μg
Datasheet
Datasheet
Recommended SIAH1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN5648193
Quantity
96 tests
Datasheet
Datasheet
Recommended SIAH1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7122729
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1319973
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1319975
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our SIAH1 products
: "Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype." in: Oncotarget, Vol. 5, Issue 24, pp. 12509-27, (2015) (PubMed).: "Disruption of the nuclear p53-GAPDH complex protects against ischemia-induced neuronal damage." in: Molecular brain, Vol. 7, pp. 20, (2014) (PubMed).
: "Sphingosine 1-phosphate induces differentiation of mesoangioblasts towards smooth muscle. A role for GATA6." in: PLoS ONE, Vol. 6, Issue 5, pp. e20389, (2011) (PubMed).
: "BAG1 modulates huntingtin toxicity, aggregation, degradation, and subcellular distribution." in: Journal of neurochemistry, Vol. 111, Issue 3, pp. 801-7, (2009) (PubMed).
: "A designer axially chiral amino sulfonamide as an efficient organocatalyst for direct asymmetric anti-selective Mannich reactions and syn-selective cross-aldol reactions." in: Chemistry (Weinheim an der Bergstrasse, Germany), Vol. 15, Issue 27, pp. 6678-87, (2009) (PubMed).
: "Regulation of beta-catenin by a novel nongenomic action of thyroid hormone beta receptor." in: Molecular and cellular biology, Vol. 28, Issue 14, pp. 4598-608, (2008) (PubMed).
: "Hypoxia-inducible factors in the first trimester human lung." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 55, Issue 4, pp. 355-63, (2007) (PubMed).
: "Siah-1L, a novel transcript variant belonging to the human Siah family of proteins, regulates beta-catenin activity in a p53-dependent manner." in: Oncogene, Vol. 23, Issue 45, pp. 7593-600, (2004) (PubMed).
: "Siah ubiquitin ligase is structurally related to TRAF and modulates TNF-alpha signaling." in: Nature structural biology, Vol. 9, Issue 1, pp. 68-75, (2001) (PubMed).
: "Siah-1 binds and regulates the function of Numb." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 26, pp. 15067-72, (2001) (PubMed).
Synonyms and alternative names related to SIAH1
E3 ubiquitin-protein ligase Siah1 (Tsp_03055), E3 ubiquitin-protein ligase siah-1 (siah-1), siah E3 ubiquitin protein ligase 1 (Siah1), siah E3 ubiquitin protein ligase 1 (siah1), siah E3 ubiquitin protein ligase 1 (SIAH1), siah E3 ubiquitin protein ligase 1 L homeolog (siah1.L), id:ibd2635, SIAH, siah, Siah1, Siah1a, SIAH1A, zgc:56026Protein level used designations for SIAH1
- E3 ubiquitin-protein ligase Siah1
- E3 ubiquitin-protein ligase SIAH1
- seven in absentia homolog 1
- siah-1
- siah-1a
- seven in absentia 1A
- seven in absentia-like protein 1
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