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This gene encodes a sucrase-isomaltase enzyme that is expressed in the intestinal brush border. The encoded protein is synthesized as a precursor protein that is cleaved by pancreatic proteases into two enzymatic subunits sucrase and isomaltase. These two subunits heterodimerize to form the sucrose-isomaltase complex. This complex is essential for the digestion of dietary carbohydrates including starch, sucrose and isomaltose. Mutations in this gene are the cause of congenital sucrase-isomaltase deficiency.[provided by RefSeq, Apr 2010].
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Recommended SI Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN635778
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN2458898
Quantity
100 μL
Datasheet
Datasheet
Synonyms and alternative names related to SI
sucrase-isomaltase (SI), sucrase isomaltase (alpha-glucosidase) (Sis), sucrase-isomaltase (Si), 2010204N08Rik, SI, Si-s, SUCIMALProtein level used designations for SI
- oligosaccharide alpha-1,6-glucosidase
- sucrase-isomaltase, intestinal
- alpha-glucosidase
- sucrase isomaltase, structural
- sucrase-isomaltase
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