SHMT2 Products
(serine Hydroxymethyltransferase 2 (Mitochondrial) (SHMT2))
Categories
This gene encodes the mitochondrial form of a pyridoxal phosphate-dependent enzyme that catalyzes the reversible reaction of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. The encoded product is primarily responsible for glycine synthesis. The activity of the encoded protein has been suggested to be the primary source of intracellular glycine. The gene which encodes the cytosolic form of this enzyme is located on chromosome 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009].
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Featured SHMT2 Categories
SHMT2 Antibodies
High quality antibodies with extensive validation data.
SHMT2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SHMT2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (8)
Cat. No.
ABIN7443701
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, IF
Validations
- (6)
Cat. No.
ABIN7255944
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF, IP
Validations
- (6)
Cat. No.
ABIN3021747
Quantity
100 μL
Datasheet
Datasheet
Recommended SHMT2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6232362
Quantity
96 tests
Datasheet
Datasheet
Recommended SHMT2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125035
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1319956
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1319955
Quantity
25 μg
Datasheet
Datasheet
Latest Publications for our SHMT2 products
: "SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance." in: Nature, Vol. 520, Issue 7547, pp. 363-7, (2015) (PubMed).: "Differentially expressed proteins in malignant and benign adrenocortical tumors." in: PLoS ONE, Vol. 9, Issue 2, pp. e87951, (2014) (PubMed).
Synonyms and alternative names related to SHMT2
serine hydroxymethyltransferase 2 (SHMT2), serine hydroxymethyltransferase 2 (mitochondrial) (Chro.80302), serine hydroxymethyltransferase 2 (mitochondrial) (Shmt2), serine hydroxymethyltransferase 2 (Shmt2), serine hydroxymethyltransferase 2 (mitochondrial) (shmt2), serine hydroxymethyltransferase 2 (mitochondrial) L homeolog (shmt2.L), serine hydroxymethyltransferase, mitochondrial-like (SHMT), 2700043D08Rik, AA408223, AA986903, GLYA, SHMTProtein level used designations for SHMT2
- GLY A+
- glycine auxotroph A, human complement for hamster
- glycine hydroxymethyltransferase
- serine aldolase
- serine hydroxymethylase
- serine hydroxymethyltransferase, mitochondrial
- serine methylase
- threonine aldolase
- SHMT
- serine hydroxymethyltransferase 2 (mitochondrial)
- mitochondrial serine hydroxymethyltransferase
- Glycine hydroxymethyltransferase
- Serine methylase
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