SHB Products
(Src Homology 2 Domain Containing Adaptor Protein B (SHB))
Categories
Adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. May play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. May also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic- FGF and NGF-induced signaling cascades. May also regulate IRS1 and IRS2 signaling in insulin-producing cells.
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Featured SHB Categories
SHB Antibodies
High quality antibodies with extensive validation data.
SHB Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SHB Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (5)
Cat. No.
ABIN2565895
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), FACS
Validations
- (3)
Cat. No.
ABIN6242628
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, ICC, IF
Validations
- (2)
Cat. No.
ABIN6257494
Quantity
100 μL
Datasheet
Datasheet
Recommended SHB Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3123689
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN2731982
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our SHB products
: "Interaction of SH2-Bbeta with RET is involved in signaling of GDNF-induced neurite outgrowth." in: Journal of cell science, Vol. 119, Issue Pt 8, pp. 1666-76, (2006) (PubMed).: "SHB and angiogenic factors promote ES cell differentiation to insulin-producing cells." in: Biochemical and biophysical research communications, Vol. 344, Issue 2, pp. 517-24, (2006) (PubMed).
: "The SHB adapter protein is required for normal maturation of mesoderm during in vitro differentiation of embryonic stem cells." in: The Journal of biological chemistry, Vol. 281, Issue 45, pp. 34484-91, (2006) (PubMed).
Synonyms and alternative names related to SHB
SH2 domain containing adaptor protein B (SHB), SH2 domain containing adaptor protein B (Shb), src homology 2 domain-containing transforming protein B (Shb), bA3J10.2, BC028832, RGD1565350, RP11-3J10.8, SHBProtein level used designations for SHB
- Src homology 2 domain containing adaptor protein B
- SH2 domain-containing adapter protein B-like
- SH2 domain-containing adapter protein B
- SHB (Src homology 2 domain containing) adaptor protein B
- SHB adaptor protein (a Src homology 2 protein)
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