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SH2B1 Products

(SH2B Adaptor Protein 1 (SH2B1))

Categories

This gene encodes a member of the SH2-domain containing mediators family. The encoded protein mediates activation of various kinases and may function in cytokine and growth factor receptor signaling and cellular transformation. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2009].

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Featured SH2B1 Categories

SH2B1 Antibodies

High quality antibodies with extensive validation data.

SH2B1 ELISA Kits

Reliable ELISA kits for a wide range of species.

SH2B1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SH2B1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application IHC, IF
Validations
  • (4)
Cat. No. ABIN7261518
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (4)
Cat. No. ABIN565207
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (4)
Cat. No. ABIN525522
Quantity 50 μg
Datasheet Datasheet

Recommended SH2B1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4884508
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6384958
Quantity 96 tests
Datasheet Datasheet

Recommended SH2B1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1319857
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1319855
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3095379
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our SH2B1 products

OBrien, OShea, Carter-Su: "SH2-B family members differentially regulate JAK family tyrosine kinases." in: The Journal of biological chemistry, Vol. 277, Issue 10, pp. 8673-81, (2002) (PubMed).

Herrington, Diakonova, Rui, Gunter, Carter-Su: "SH2-B is required for growth hormone-induced actin reorganization." in: The Journal of biological chemistry, Vol. 275, Issue 17, pp. 13126-33, (2000) (PubMed).

Qian, Riccio, Zhang, Ginty: "Identification and characterization of novel substrates of Trk receptors in developing neurons." in: Neuron, Vol. 21, Issue 5, pp. 1017-29, (1999) (PubMed).

Rothenberg: "Bioethics commission to review gene patenting." in: Bio/technology (Nature Publishing Company), Vol. 13, Issue 13, pp. 1431, (1998) (PubMed).

Riedel, Wang, Hansen, Yousaf: "PSM, an insulin-dependent, pro-rich, PH, SH2 domain containing partner of the insulin receptor." in: Journal of biochemistry, Vol. 122, Issue 6, pp. 1105-13, (1998) (PubMed).

Rui, Carter-Su: "Platelet-derived growth factor (PDGF) stimulates the association of SH2-Bbeta with PDGF receptor and phosphorylation of SH2-Bbeta." in: The Journal of biological chemistry, Vol. 273, Issue 33, pp. 21239-45, (1998) (PubMed).

Osborne, Dalton, Kochan: "The yeast tribrid system--genetic detection of trans-phosphorylated ITAM-SH2-interactions." in: Bio/technology (Nature Publishing Company), Vol. 13, Issue 13, pp. 1474-8, (1998) (PubMed).

Rui, Mathews, Hotta, Gustafson, Carter-Su: "Identification of SH2-Bbeta as a substrate of the tyrosine kinase JAK2 involved in growth hormone signaling." in: Molecular and cellular biology, Vol. 17, Issue 11, pp. 6633-44, (1997) (PubMed).

Wang, Yaciuk, Ricciardi, Green, Yokoyama, Moran: "The E1A products of oncogenic adenovirus serotype 12 include amino-terminally modified forms able to bind the retinoblastoma protein but not p300." in: Journal of virology, Vol. 67, Issue 8, pp. 4804-13, (1993) (PubMed).

Rikitake, Moran: "DNA-binding properties of the E1A-associated 300-kilodalton protein." in: Molecular and cellular biology, Vol. 12, Issue 6, pp. 2826-36, (1992) (PubMed).

Synonyms and alternative names related to SH2B1

SH2B adaptor protein 1 (SH2B1), SH2B adaptor protein 1 (sh2b1), SH2B adaptor protein 1 (Sh2b1), AI425885, C530001K22Rik, Irip, mKIAA1299, PSM, SH2-B, Sh2-b, SH2-Bb, SH2B, Sh2b, SH2B3, Sh2bpsm1, zgc:158474

Protein level used designations for SH2B1

  • SH2B adapter protein 1
  • SH2B adaptor protein 1
  • SH2B adapter protein 1-like
  • SH2 domain-containing protein 1B
  • SH2 domain-containing putative adapter SH2-B
  • SH2-B signaling protein
  • pro-rich, PH and SH2 domain-containing signaling mediator
  • PSM
  • SH2-B PH domain containing signaling mediator 1
  • SH2-B PH domain-containing signaling mediator 1
  • fceRI gamma-chain-interacting protein SH2-B
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