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SGEF Products

(rho Guanine Nucleotide Exchange Factor (GEF) 26 (ARHGEF26))

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This gene encodes a member of the Rho-guanine nucleotide exchange factor (Rho-GEF) family. These proteins regulate Rho GTPases by catalyzing the exchange of GDP for GTP. The encoded protein specifically activates RhoG and plays a role in the promotion of macropinocytosis. Underexpression of the encoded protein may be a predictive marker of chemoresistant disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011].

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SGEF Antibodies

High quality antibodies with extensive validation data.

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Synonyms and alternative names related to SGEF

Rho guanine nucleotide exchange factor (GEF) 26 (Arhgef26), Rho guanine nucleotide exchange factor 26 (Arhgef26), Rho guanine nucleotide exchange factor 26 (ARHGEF26), 4631416L12Rik, 8430436L14Rik, AI303572, AW491953, CSGEF, HMFN1864, RGD1562559, SGEF, Sgef

Protein level used designations for SGEF

  • Src homology 3 domain-containing guanine nucleotide exchange factor
  • rho guanine nucleotide exchange factor 26
  • SH3 domain-containing guanine exchange factor
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