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SGCG Products

(Sarcoglycan, gamma (35kDa Dystrophin-Associated Glycoprotein) (SGCG))

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This gene encodes gamma-sarcoglycan, one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin. The dystrophin-glycoprotein complex (DGC) spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Defects in the encoded protein can lead to early onset autosomal recessive muscular dystrophy, in particular limb-girdle muscular dystrophy, type 2C (LGMD2C). [provided by RefSeq, Oct 2008].

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Featured SGCG Categories

SGCG Antibodies

High quality antibodies with extensive validation data.

SGCG Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SGCG Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF, ICC
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Cat. No. ABIN6265040
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (5)
  • (2)
Cat. No. ABIN1881799
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IP
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  • (3)
Cat. No. ABIN520158
Quantity 100 μL
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Recommended SGCG ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6231046
Quantity 96 tests
Datasheet Datasheet

Recommended SGCG Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1319810
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
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  • (1)
Cat. No. ABIN1319808
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3099671
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our SGCG products

Chrzanowski, Vohra, Lee-McMullen, Batra, Spradlin, Morales, Forbes, Vandenborne, Barton, Walter: "Contrast-Enhanced Near-Infrared Optical Imaging Detects Exacerbation and Amelioration of Murine Muscular Dystrophy." in: Molecular imaging, Vol. 16, pp. 1536012117732439, (2018) (PubMed).

Rafii, Hagiwara, Mercado, Seo, Xu, Dugan, Owens, Hook, McQuillan, Young, Fallon: "Biglycan binds to alpha- and gamma-sarcoglycan and regulates their expression during development." in: Journal of cellular physiology, Vol. 209, Issue 2, pp. 439-47, (2006) (PubMed).

Dunham, Matthews, Burton, Ashurst, Howe, Ashcroft, Beare, Burford, Hunt, Griffiths-Jones, Jones, Keenan, Oliver, Scott, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey et al.: "The DNA sequence and analysis of human chromosome 13. ..." in: Nature, Vol. 428, Issue 6982, pp. 522-8, (2004) (PubMed).

Thompson, Chan, Hack, Brosius, Rajala, Lidov, McNally, Watkins, Kunkel: "Filamin 2 (FLN2): A muscle-specific sarcoglycan interacting protein." in: The Journal of cell biology, Vol. 148, Issue 1, pp. 115-26, (2000) (PubMed).

Piccolo, Jeanpierre, Leturcq, Dodé, Azibi, Toutain, Merlini, Jarre, Navarro, Krishnamoorthy, Tomé, Urtizberea, Beckmann, Campbell, Kaplan: "A founder mutation in the gamma-sarcoglycan gene of gypsies possibly predating their migration out of India." in: Human molecular genetics, Vol. 5, Issue 12, pp. 2019-22, (1997) (PubMed).

McNally, Passos-Bueno, Bönnemann, Vainzof, de Sá Moreira, Lidov, Othmane, Denton, Vance, Zatz, Kunkel: "Mild and severe muscular dystrophy caused by a single gamma-sarcoglycan mutation." in: American journal of human genetics, Vol. 59, Issue 5, pp. 1040-7, (1996) (PubMed).

Noguchi, McNally, Ben Othmane, Hagiwara, Mizuno, Yoshida, Yamamoto, Bönnemann, Gussoni, Denton, Kyriakides, Middleton, Hentati, Ben Hamida, Nonaka, Vance, Kunkel, Ozawa: "Mutations in the dystrophin-associated protein gamma-sarcoglycan in chromosome 13 muscular dystrophy." in: Science (New York, N.Y.), Vol. 270, Issue 5237, pp. 819-22, (1995) (PubMed).

Synonyms and alternative names related to SGCG

sarcoglycan, gamma (sgcg), sarcoglycan gamma (SGCG), sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) (SGCG), sarcoglycan gamma (Sgcg), sarcoglycan, gamma (dystrophin-associated glycoprotein) (Sgcg), sarcoglycan, gamma (Sgcg), 35DAG, 35kDa, 5430420E18Rik, A4, AI642964, DAGA4, DMDA, DMDA1, Gamma-SG, gamma-SG, LGMD2C, MAM, SCARMD2, SCG3, TYPE, zgc:100924

Protein level used designations for SGCG

  • gamma-sarcoglycan
  • 35 kDa dystrophin-associated glycoprotein
  • 35DAG
  • 35kD dystrophin-associated glycoprotein
  • gamma sarcoglycan
  • gamma-SG
  • sgcg gene for gamma-sarcoglycan
  • sarcoglycan, gamma (35kD dystrophin-associated glycoprotein)
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