SGCB Products
(Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) (SGCB))
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This gene encodes a member of the sarcoglycan family. Sarcoglycans are transmembrane components in the dystrophin-glycoprotein complex which help stabilize the muscle fiber membranes and link the muscle cytoskeleton to the extracellular matrix. Mutations in this gene have been associated with limb-girdle muscular dystrophy.[provided by RefSeq, Oct 2008].
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Featured SGCB Categories
SGCB Antibodies
High quality antibodies with extensive validation data.
SGCB Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SGCB Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), IF
Validations
- (6)
Cat. No.
ABIN562847
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (4)
Cat. No.
ABIN738051
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC
Validations
- (3)
Cat. No.
ABIN7262903
Quantity
200 μL
Datasheet
Datasheet
Recommended SGCB ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Sandwich ELISA
Validations
Cat. No.
ABIN419867
Quantity
96 tests
Datasheet
Datasheet
Recommended SGCB Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124984
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1319800
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1319798
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our SGCB products
: "Defective Flux of Thrombospondin-4 through the Secretory Pathway Impairs Cardiomyocyte Membrane Stability and Causes Cardiomyopathy." in: Molecular and cellular biology, Vol. 38, Issue 14, (2018) (PubMed).: "Dystrophin Expressing Chimeric (DEC) Human Cells Provide a Potential Therapy for Duchenne Muscular Dystrophy." in: Stem cell reviews, Vol. 14, Issue 3, pp. 370-384, (2018) (PubMed).
: "Systemic AAV-Mediated β-Sarcoglycan Delivery Targeting Cardiac and Skeletal Muscle Ameliorates Histological and Functional Deficits in LGMD2E Mice." in: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 25, Issue 4, pp. 855-869, (2017) (PubMed).
: "β-Sarcoglycan gene transfer decreases fibrosis and restores force in LGMD2E mice." in: Gene therapy, Vol. 23, Issue 1, pp. 57-66, (2016) (PubMed).
: "Thrombospondin expression in myofibers stabilizes muscle membranes." in: eLife, Vol. 5, (2016) (PubMed).
: "Evidence of associations of APOBEC3B gene deletion with susceptibility to persistent HBV infection and hepatocellular carcinoma." in: Human molecular genetics, Vol. 22, Issue 6, pp. 1262-9, (2013) (PubMed).
: "SGCE missense mutations that cause myoclonus-dystonia syndrome impair epsilon-sarcoglycan trafficking to the plasma membrane: modulation by ubiquitination and torsinA." in: Human molecular genetics, Vol. 16, Issue 3, pp. 327-42, (2007) (PubMed).
Synonyms and alternative names related to SGCB
sarcoglycan beta (SGCB), sarcoglycan, beta (dystrophin-associated glycoprotein) (Sgcb), Sarcoglycan beta (Scgbeta), SarcoGlycaN (sgn-1), uncharacterized LOC5567384 (LOC5567384), beta-sarcoglycan (CpipJ_CPIJ006944), sarcoglycan, beta (Sgcb), sarcoglycan beta L homeolog (sgcb.L), sarcoglycan beta (Sgcb), sarcoglycan, beta (dystrophin-associated glycoprotein) (sgcb), 43kDa, A3b, AI747103, AI844814, beta-sarcoglycan, beta-SG, CG5657, Dmel\\CG5657, DmSCG-beta, dscgbeta, fa03a05, LGMD2E, scg-beta, SGC, wu:fa03a05, zgc:110833Protein level used designations for SGCB
- 43 kDa dystrophin-associated glycoprotein
- 43DAG
- beta-SG
- beta-sarcoglycan
- beta-sarcoglycan(43kD dystrophin-associated glycoprotein)
- limb girdle muscular dystrophy 2E (non-linked families)
- sarcoglycan, beta (43kD dystrophin-associated glycoprotein)
- sarcoglycan beta
- CG5657-PA
- Scgbeta-PA
- beta-sarcolgycan
- SarcoGlycaN family member (sgn-1)
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