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SGCA Products

(Sarcoglycan, alpha (50kDa Dystrophin-Associated Glycoprotein) (SGCA))

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This gene encodes a component of the dystrophin-glycoprotein complex (DGC), which is critical to the stability of muscle fiber membranes and to the linking of the actin cytoskeleton to the extracellular matrix. Its expression is thought to be restricted to striated muscle. Mutations in this gene result in type 2D autosomal recessive limb-girdle muscular dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008].

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Featured SGCA Categories

SGCA Antibodies

High quality antibodies with extensive validation data.

SGCA Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SGCA Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (4)
Cat. No. ABIN7143931
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (4)
Cat. No. ABIN1682687
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (3)
Cat. No. ABIN6258888
Quantity 100 μL
Datasheet Datasheet

Recommended SGCA ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6229256
Quantity 96 tests
Datasheet Datasheet

Recommended SGCA Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1319794
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1319796
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7420366
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our SGCA products

Kounnis, Ioachim, Svoboda, Tzakos, Sainis, Thalhammer, Steiner, Briasoulis: "Expression of organic anion-transporting polypeptides 1B3, 1B1, and 1A2 in human pancreatic cancer reveals a new class of potential therapeutic targets." in: OncoTargets and therapy, Vol. 4, pp. 27-32, (2011) (PubMed).

Esapa, Waite, Locke, Benson, Kraus, McIlhinney, Sillitoe, Beesley, Blake: "SGCE missense mutations that cause myoclonus-dystonia syndrome impair epsilon-sarcoglycan trafficking to the plasma membrane: modulation by ubiquitination and torsinA." in: Human molecular genetics, Vol. 16, Issue 3, pp. 327-42, (2007) (PubMed).

Synonyms and alternative names related to SGCA

sarcoglycan alpha (SGCA), sarcoglycan, alpha (dystrophin-associated glycoprotein) (Sgca), sarcoglycan, alpha (Sgca), 50-DAG, 50DAG, A2, adhalin, ADL, Asg, DAG2, DMDA2, LGMD2D, SCARMD1, Sgca

Protein level used designations for SGCA

  • 50 kDa dystrophin-associated glycoprotein
  • 50DAG
  • adhalin
  • alpha-SG
  • alpha-sarcoglycan
  • dystroglycan-2
  • 50kD DAG
  • sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)
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