SFTPB Products
(Surfactant Protein B (SFTPB))
Categories
This gene encodes the pulmonary-associated surfactant protein B (SPB), an amphipathic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. The SPB enhances the rate of spreading and increases the stability of surfactant monolayers in vitro. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 1, also called pulmonary alveolar proteinosis due to surfactant protein B deficiency, and are associated with fatal respiratory distress in the neonatal period. Alternatively spliced transcript variants encoding the same protein have been identified.[provided by RefSeq, Feb 2010].
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Featured SFTPB Categories
SFTPB Antibodies
High quality antibodies with extensive validation data.
SFTPB ELISA Kits
Reliable ELISA kits for a wide range of species.
SFTPB Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SFTPB Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (6)
Cat. No.
ABIN7433858
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (4)
Cat. No.
ABIN7437509
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP
Validations
- (3)
Cat. No.
ABIN948458
Quantity
100 μL
Datasheet
Datasheet
Recommended SFTPB ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (16)
- (1)
Cat. No.
ABIN6959773
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (8)
- (1)
Cat. No.
ABIN6959774
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969781
Quantity
96 tests
Datasheet
Datasheet
Recommended SFTPB Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1319778
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7394432
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7401116
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our SFTPB products
: "Chronic lung injury and impaired pulmonary function in a mouse model of acid ceramidase deficiency." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 314, Issue 3, pp. L406-L420, (2019) (PubMed).: "Serum Surfactant Protein Levels in Patients Admitted to the Hospital with Acute COPD Exacerbation." in: Lung, Vol. 196, Issue 2, pp. 201-205, (2019) (PubMed).
: "Diving and pulmonary physiology: Surfactant binding protein, lung fluid and cardiopulmonary test changes in professional divers." in: Respiratory physiology & neurobiology, Vol. 243, pp. 27-31, (2018) (PubMed).
: "Surfactant proteins changes after acute hemodynamic improvement in patients with advanced chronic heart failure treated with Levosimendan." in: Respiratory physiology & neurobiology, Vol. 252-253, pp. 47-51, (2018) (PubMed).
: "Effects and molecular mechanisms of intrauterine infection/inflammation on lung development." in: Respiratory research, Vol. 19, Issue 1, pp. 93, (2018) (PubMed).
: "Correlations of Ventricular Enlargement with Rheologically Active Surfactant Proteins in Cerebrospinal Fluid." in: Frontiers in aging neuroscience, Vol. 8, pp. 324, (2017) (PubMed).
: "Trinucleotide repeat containing 6c (TNRC6c) is essential for microvascular maturation during distal airspace sacculation in the developing lung." in: Developmental biology, Vol. 430, Issue 1, pp. 214-223, (2017) (PubMed).
: "Surfactant Protein B Suppresses Lung Cancer Progression by Inhibiting Secretory Phospholipase A2 Activity and Arachidonic Acid Production." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 42, Issue 4, pp. 1684-1700, (2017) (PubMed).
: "Serum Levels of Surfactant Proteins in Patients with Combined Pulmonary Fibrosis and Emphysema (CPFE)." in: PLoS ONE, Vol. 11, Issue 6, pp. e0157789, (2016) (PubMed).
: "The Cerebral Surfactant System and Its Alteration in Hydrocephalic Conditions." in: PLoS ONE, Vol. 11, Issue 9, pp. e0160680, (2016) (PubMed).
Synonyms and alternative names related to SFTPB
surfactant protein B (SFTPB), surfactant associated protein B (Sftpb), surfactant protein B (Sftpb), surfactant, pulmonary-associated protein B L homeolog (sftpb.L), AI562151, PSP-B, SF-B, SFTB3, Sftp-3, SFTP3, Sftp3, SFTPB, sftpb, SMDP1, SP-B, Sp-b, xSP-BProtein level used designations for SFTPB
- 18 kDa pulmonary-surfactant protein
- 6 kDa protein
- pulmonary surfactant-associated protein B
- pulmonary surfactant-associated proteolipid SPL(Phe)
- surfactant associated protein B
- surfactant pulmonary-associated protein B
- surfactant, pulmonary-associated protein B
- SP-B
- surfactant protein B
- surfactant, pulmonary-associated protein B L homeolog
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