SF3B4 Products
(Splicing Factor 3b, Subunit 4, 49kDa (SF3B4))
Categories
This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA. [provided by RefSeq, Jul 2008].
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Featured SF3B4 Categories
SF3B4 Antibodies
High quality antibodies with extensive validation data.
SF3B4 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SF3B4 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (3)
Cat. No.
ABIN6259186
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (3)
Cat. No.
ABIN523675
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7188043
Quantity
100 μg
Datasheet
Datasheet
Recommended SF3B4 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6232342
Quantity
96 tests
Datasheet
Datasheet
Recommended SF3B4 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1319717
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1319719
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Schizosaccharomyces pombe
Source
Yeast
Validations
Cat. No.
ABIN1592179
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our SF3B4 products
: "Many sequence variants affecting diversity of adult human height." in: Nature genetics, Vol. 40, Issue 5, pp. 609-15, (2008) (PubMed).: "Splicing factor 3b subunit 4 binds BMPR-IA and inhibits osteochondral cell differentiation." in: The Journal of biological chemistry, Vol. 282, Issue 28, pp. 20728-38, (2007) (PubMed).
: "Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening." in: Proteomics, Vol. 7, Issue 11, pp. 1775-85, (2007) (PubMed).
: "The prespliceosome components SAP 49 and SAP 145 interact in a complex implicated in tethering U2 snRNP to the branch site." in: Genes & development, Vol. 8, Issue 16, pp. 1974-83, (1994) (PubMed).
Synonyms and alternative names related to SF3B4
Splicing factor 3B subunit 4 (sap-49), splicing factor 3b, subunit 4 (sf3b4), splicing factor 3b, subunit 4 (Sf3b4), splicing factor 3b subunit 4 S homeolog (sf3b4.S), splicing factor 3b subunit 4 (SF3B4), 49kDa, AFD1, chunp6902, fb36a04, Hsh49, Sap49, SAP49, SF3b49, SF3b50, spx, wu:fb36a04Protein level used designations for SF3B4
- splicing factor 3B subunit 4
- splicing factor 3b, subunit 4, 49kD
- spliceosome associated protein 49
- SAP 49
- SF3b50
- pre-mRNA-splicing factor SF3b 49 kDa subunit
- spliceosomal protein
- spliceosome-associated protein (U2 snRNP)
- spliceosome-associated protein 49
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