Rabbit anti-Human IgG4 Antibody
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- Target See all IgG4 products
- IgG4
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Monoclonal
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Application
- Western Blotting (WB)
- Cross-Reactivity
- Human
- Purification
- Purified by Protein A.
- Immunogen
- Full length protein
- Clone
- 1A8
- Isotype
- IgG
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Rabbit anti-Human IgG4 (AA 222-327) antibody
WB, IHC, IP, IF/ICC Polyclonal unconjugated
Mouse anti-Human IgG4 (pFc' Region) antibody (HRP)WB, IHC, ELISA Monoclonal HP6023 IgG3 HRP
Mouse anti-Human IgG4 (pFc' Region) antibody (Alkaline Phosphatase (AP))WB, IHC, ELISA Monoclonal HP6023 IgG3 Alkaline Phosphatase (AP)
Mouse anti-Human IgG4 (Fc Region) antibody (HRP)WB, IHC, ELISA Monoclonal HP6025 IgG1 HRP
Mouse anti-Human IgG4 (Fc Region) antibody (Alkaline Phosphatase (AP))WB, IHC, ELISA Monoclonal HP6025 IgG1 Alkaline Phosphatase (AP)
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- Application Notes
- WB 1:300-5000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C for 12 months.
- Expiry Date
- 12 months
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- Target
- IgG4
- Abstract
- IgG4 Products
- Target Type
- Antibody
- Background
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Synonyms: Ig gamma-4 chain C region, IGHG4, Immunoglobulin heavy constant gamma 4
Background: Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268).
- UniProt
- P01861
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