Mouse anti-Human IgA (Free & Bound), (Secretory Component) Antibody (FITC)
-
- Target See all IgA products
- IgA
-
Binding Specificity
- Free & Bound, Secretory Component
-
Reactivity
- Human
-
Host
- Mouse
-
Clonality
- Monoclonal
-
Conjugate
- FITC
-
Application
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)
- Cross-Reactivity (Details)
- Species reactivity (tested):Human.
- Characteristics
- Molar Ratio: Fluorochrome/IgG: aprox. 2.0
- Immunogen
- Highly purified Secretory component isolated from Human milk.
- Clone
- NI 194-4 (A89-039)
- Isotype
- IgG1
-
Goat anti-Human IgA (Heavy Chain) antibody (Biotin)
ELISA, WB, FACS Polyclonal IgG Biotin
Rabbit anti-Human IgA (Heavy Chain) antibody - PreadsorbedELISA, IHC, WB Polyclonal IgG unconjugated
Goat anti-Human IgA (Heavy Chain) antibody (Alkaline Phosphatase (AP))ELISA, WB Polyclonal IgG Alkaline Phosphatase (AP)
Rabbit anti-Human IgA (Heavy Chain) antibody (Biotin) - PreadsorbedELISA, IHC, WB Polyclonal IgG Biotin
Goat anti-Human IgA (Heavy Chain) antibody (Alkaline Phosphatase (AP)) - PreadsorbedELISA, IHC, WB Polyclonal IgG Alkaline Phosphatase (AP)
Rabbit anti-Human IgA (Chain alpha), (Heavy Chain) antibodyELISA, IHC, WB unconjugated
-
- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
-
Absorption / Emission: 492 nm / 515 nm
- Restrictions
- For Research Use only
-
- Reconstitution
- Restore by adding 0.5 mL sterile distilled water.
- Concentration
- 0.4 mg/mL
- Buffer
- PBS, pH 7.2 without preservatives and foreign proteins.
- Preservative
- Without preservative
- Handling Advice
-
Product is photosensitive and should be protected from light.
Avoid repeated freezing and thawing. - Storage
- 4 °C/-20 °C
- Storage Comment
- Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one week or (in aliquots) at -28 °C for longer.
-
- Target
- IgA
- Abstract
- IgA Products
- Target Type
- Antibody
- Background
- Secretory Component Glycoprotein is an epithelial transport receptor for polymeric IgA and IgM. Antibody to secretory component has been shown to be useful for identifying glandular carcinomas. Defects in Secretory Component Glycoprotein are the cause of lipoid proteinosis (LiP), also known as lipoid proteinosis of Urbach and Wiethe or hyalinosis cutis et mucosae. LiP is a rare autosomal recessive disorder characterized by generalized thickening of skin, mucosae and certain viscera. Classical features include beaded eyelid papules and laryngeal infiltration leading to hoarseness. Histologically, there is widespread deposition of hyaline material and disruption/reduplication of basement membrane. Examples of positive human tissues: secretory mucosa of gastrointestinal and respiratory tract, epithelia of salivary glands, endometrium, endocervix, kidney, prostate, mammary gland.Synonyms: Human Immunoglobulin A
-
