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SETDB2 Products

(SET Domain, Bifurcated 2 (SETDB2))

Categories

Proteins that contain a SET domain, such as SETDB2, modulate gene expression epigenetically through histone H3 (see MIM 601128) methylation. SETDB2 is likely a histone H3 methyltransferase, as it contains both the active site and flanking cysteine residues required for catalytic activity (Zhang et al., 2003 [PubMed 12754510]).[supplied by OMIM, Mar 2008].

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Featured SETDB2 Categories

SETDB2 Antibodies

High quality antibodies with extensive validation data.

SETDB2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SETDB2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (3)
Cat. No. ABIN184878
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC, IF, ICC
Validations
  • (2)
Cat. No. ABIN6258755
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN529503
Quantity 50 μg
Datasheet Datasheet

Recommended SETDB2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6228062
Quantity 96 tests
Datasheet Datasheet

Recommended SETDB2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1319689
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1319687
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3095317
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our SETDB2 products

Roy, Ghosh, Kumar, Chandran: "IFI16, a nuclear innate immune DNA sensor, mediates epigenetic silencing of herpesvirus genomes by its association with H3K9 methyltransferases SUV39H1 and GLP." in: eLife, Vol. 8, (2019) (PubMed).

Zhang, Leaves, Anderson, Ponting, Broxholme, Holt, Edser, Bhattacharyya, Dunham, Adcock, Pulleyn, Barnes, Harper, Abecasis, Cardon, White, Burton, Matthews, Mott, Ross, Cox, Moffatt, Cookson: "Positional cloning of a quantitative trait locus on chromosome 13q14 that influences immunoglobulin E levels and asthma." in: Nature genetics, Vol. 34, Issue 2, pp. 181-6, (2003) (PubMed).

Mabuchi, Fujii, Calin, Alder, Negrini, Rassenti, Kipps, Bullrich, Croce: "Cloning and characterization of CLLD6, CLLD7, and CLLD8, novel candidate genes for leukemogenesis at chromosome 13q14, a region commonly deleted in B-cell chronic lymphocytic leukemia." in: Cancer research, Vol. 61, Issue 7, pp. 2870-7, (2001) (PubMed).

Synonyms and alternative names related to SETDB2

SET domain bifurcated 2 (SETDB2), SET domain, bifurcated 2 (Setdb2), C13orf4, CLLD8, Clld8, CLLL8, Gm293, KMT1F

Protein level used designations for SETDB2

  • chronic lymphocytic leukemia deletion region 8
  • chronic lymphocytic leukemia deletion region gene 8 protein
  • histone-lysine N-methyltransferase SETDB2
  • lysine N-methyltransferase 1F
  • Setdb2-Phf11-1-Phf11-2 fusion
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