SETD2 Products
(SET Domain Containing 2 (SETD2))
Categories
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. [provided by RefSeq, Aug 2008].
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Featured SETD2 Categories
SETD2 Antibodies
High quality antibodies with extensive validation data.
Recommended SETD2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (4)
- (10)
Cat. No.
ABIN1682666
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, FACS
Validations
- (4)
Cat. No.
ABIN7193416
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, FACS
Validations
- (1)
- (2)
Cat. No.
ABIN238587
Quantity
100 μg
Datasheet
Datasheet
Recommended SETD2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6205033
Quantity
96 tests
Datasheet
Datasheet
Recommended SETD2 Proteins
Latest Publications for our SETD2 products
: "HnRNPL inhibits the osteogenic differentiation of PDLCs stimulated by SrCl2 through repressing Setd2." in: Journal of cellular and molecular medicine, Vol. 23, Issue 4, pp. 2667-2677, (2020) (PubMed).: "H3K36me3-mediated mismatch repair preferentially protects actively transcribed genes from mutation." in: The Journal of biological chemistry, Vol. 293, Issue 20, pp. 7811-7823, (2019) (PubMed).
: "Setd2 is associated with strontium-induced bone regeneration." in: Acta biomaterialia, Vol. 53, pp. 495-505, (2018) (PubMed).
: "Methyltransferase SETD2-Mediated Methylation of STAT1 Is Critical for Interferon Antiviral Activity." in: Cell, Vol. 170, Issue 3, pp. 492-506.e14, (2017) (PubMed).
: "SPOP-containing complex regulates SETD2 stability and H3K36me3-coupled alternative splicing." in: Nucleic acids research, Vol. 45, Issue 1, pp. 92-105, (2017) (PubMed).
: "Histone methyltransferase Setd2 is critical for the proliferation and differentiation of myoblasts." in: Biochimica et biophysica acta. Molecular cell research, Vol. 1864, Issue 4, pp. 697-707, (2017) (PubMed).
: "SETD2 loss-of-function promotes renal cancer branched evolution through replication stress and impaired DNA repair. ..." in: Oncogene, Vol. 34, Issue 46, pp. 5699-708, (2015) (PubMed).
: "Promoter-exon relationship of H3 lysine 9, 27, 36 and 79 methylation on pluripotency-associated genes." in: Biochemical and biophysical research communications, Vol. 401, Issue 4, pp. 611-7, (2010) (PubMed).
: "Organization of chromatin and histone modifications at a transcription site." in: The Journal of cell biology, Vol. 177, Issue 6, pp. 957-67, (2007) (PubMed).
: "Identification and characterization of a novel human histone H3 lysine 36-specific methyltransferase." in: The Journal of biological chemistry, Vol. 280, Issue 42, pp. 35261-71, (2005) (PubMed).
Synonyms and alternative names related to SETD2
SET domain containing 2 (Setd2), SET domain containing 2 (SETD2), HBP231, HIF-1, HIP-1, HYPB, Kif9, KMT3A, p231HBP, SET2Protein level used designations for SETD2
- histone-lysine N-methyltransferase SETD2
- kinesin family member 9
- huntingtin interacting protein 1
- huntingtin yeast partner B
- huntingtin-interacting protein B
- lysine N-methyltransferase 3A
Did you look for something else?
- SETD1B
- SETD1A
- SETBP1
- SET7/9
- SET7
- SET/TAF-I
- SET Domain, Bifurcated 1
- SET Domain Containing (Lysine Methyltransferase) 8
- SET Binding Factor 2
- SET and MYND Domain Containing 2a
- SET and MYND Domain Containing 1
- Sestrin 2
- SESTD1
- SESN3
- SESN1
- Seryl-tRNA Synthetase
- serum/glucocorticoid Regulated Kinase 2
- serum/glucocorticoid Regulated Kinase 1
- Serum Amyloid A3 Pseudogene
- SERTM1
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