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SET7 Products

(SET Domain Containing 8 Pseudogene 1 (SETD8P1))

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Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. Monomethylates 'Lys-189' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates 'Lys-372' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation.

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Featured SET7 Categories

SET7 Antibodies

High quality antibodies with extensive validation data.

Recommended SET7 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (3)
Cat. No. ABIN5539110
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN387998
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC (fp), IP
Validations
Cat. No. ABIN7454780
Quantity 20 μg
Datasheet Datasheet

Recommended SET7 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125070
Quantity 50 μg
Datasheet Datasheet

Synonyms and alternative names related to SET7

SET domain containing lysine methyltransferase 7 (SETD7), SET domain containing (lysine methyltransferase) 7 (Setd7), 1600028F23Rik, H3K4MT, KMT7, mKIAA1717, SET7, Set7, SET7/9, Set7/9, SET9

Protein level used designations for SET7

  • H3-K4-HMTase SETD7
  • SET domain-containing protein 7
  • histone H3-K4 methyltransferase SETD7
  • histone H3-lysine 4-specific methyltransferase
  • histone-lysine N-methyltransferase SETD7
  • lysine N-methyltransferase 7
  • H3-K4 methyltransferase
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