SET7 Products
(SET Domain Containing 8 Pseudogene 1 (SETD8P1))
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Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. Monomethylates 'Lys-189' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates 'Lys-372' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation.
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Featured SET7 Categories
SET7 Antibodies
High quality antibodies with extensive validation data.
Recommended SET7 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p)
Validations
- (3)
Cat. No.
ABIN5539110
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN387998
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (fp), IP
Validations
Cat. No.
ABIN7454780
Quantity
20 μg
Datasheet
Datasheet
Recommended SET7 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125070
Quantity
50 μg
Datasheet
Datasheet
Synonyms and alternative names related to SET7
SET domain containing lysine methyltransferase 7 (SETD7), SET domain containing (lysine methyltransferase) 7 (Setd7), 1600028F23Rik, H3K4MT, KMT7, mKIAA1717, SET7, Set7, SET7/9, Set7/9, SET9Protein level used designations for SET7
- H3-K4-HMTase SETD7
- SET domain-containing protein 7
- histone H3-K4 methyltransferase SETD7
- histone H3-lysine 4-specific methyltransferase
- histone-lysine N-methyltransferase SETD7
- lysine N-methyltransferase 7
- H3-K4 methyltransferase
Did you look for something else?
- SET/TAF-I
- SET Domain, Bifurcated 1
- SET Domain Containing (Lysine Methyltransferase) 8
- SET Binding Factor 2
- SET and MYND Domain Containing 2a
- SET and MYND Domain Containing 1
- Sestrin 2
- SESTD1
- SESN3
- SESN1
- Seryl-tRNA Synthetase
- serum/glucocorticoid Regulated Kinase 2
- serum/glucocorticoid Regulated Kinase 1
- Serum Amyloid A3 Pseudogene
- SERTM1
- SERTAD4-AS1
- SERTAD4
- SERTAD3
- SERTAD2
- SERTAD1
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