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SESN3 Products

(Sestrin 3 (SESN3))

Categories

This gene encodes a member of the sestrin family of stress-induced proteins. The encoded protein reduces the levels of intracellular reactive oxygen species induced by activated Ras downstream of RAC-alpha serine/threonine-protein kinase (Akt) and FoxO transcription factor. The protein is required for normal regulation of blood glucose, insulin resistance and plays a role in lipid storage in obesity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012].

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Featured SESN3 Categories

SESN3 Antibodies

High quality antibodies with extensive validation data.

SESN3 ELISA Kits

Reliable ELISA kits for a wide range of species.

SESN3 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SESN3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
  • (3)
Cat. No. ABIN656403
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, ICC
Validations
  • (4)
Cat. No. ABIN2856855
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN530853
Quantity 50 μg
Datasheet Datasheet

Recommended SESN3 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970191
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970190
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959451
Quantity 96 tests
Datasheet Datasheet

Recommended SESN3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1319667
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1319669
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7398665
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our SESN3 products

Miki, Tanji, Mori, Utsumi, Sasaki, Kakita, Takahashi, Wakabayashi: "Autophagy mediators (FOXO1, SESN3 and TSC2) in Lewy body disease and aging." in: Neuroscience letters, Vol. 684, pp. 35-41, (2018) (PubMed).

Kosaka, Hongo, Miyazaki, Nishimoto, Miyajima, Oya: "Reactive oxygen species induction by cabazitaxel through inhibiting Sestrin-3 in castration resistant prostate cancer." in: Oncotarget, Vol. 8, Issue 50, pp. 87675-87683, (2017) (PubMed).

Kimball, Ravi, Gordon, Dennis, Jefferson: "Amino Acid-Induced Activation of mTORC1 in Rat Liver Is Attenuated by Short-Term Consumption of a High-Fat Diet." in: The Journal of nutrition, Vol. 145, Issue 11, pp. 2496-502, (2015) (PubMed).

Ye, Palm, Peng, King, Lindsten, Li, Koumenis, Thompson: "GCN2 sustains mTORC1 suppression upon amino acid deprivation by inducing Sestrin2." in: Genes & development, Vol. 29, Issue 22, pp. 2331-6, (2015) (PubMed).

Vakana, Arslan, Szilard, Altman, Platanias: "Regulatory effects of sestrin 3 (SESN3) in BCR-ABL expressing cells." in: PLoS ONE, Vol. 8, Issue 11, pp. e78780, (2013) (PubMed).

Synonyms and alternative names related to SESN3

sestrin 3 (SESN3), sestrin 3 (sesn3), sestrin 3 L homeolog (sesn3.L), sestrin 3 (Sesn3), 5630400E15Rik, BC003348, cb261, sb:cb261, sest3, SEST3, sestrin-3, wu:fb77c04, wu:fc41d03, wu:fd59d12, zgc:56722

Protein level used designations for SESN3

  • sestrin-3
  • sestrin 3
  • sestrin-3-like
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