SESN3 Products
(Sestrin 3 (SESN3))
Categories
This gene encodes a member of the sestrin family of stress-induced proteins. The encoded protein reduces the levels of intracellular reactive oxygen species induced by activated Ras downstream of RAC-alpha serine/threonine-protein kinase (Akt) and FoxO transcription factor. The protein is required for normal regulation of blood glucose, insulin resistance and plays a role in lipid storage in obesity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012].
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Featured SESN3 Categories
SESN3 Antibodies
High quality antibodies with extensive validation data.
SESN3 ELISA Kits
Reliable ELISA kits for a wide range of species.
SESN3 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SESN3 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (2)
- (3)
Cat. No.
ABIN656403
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, ICC
Validations
- (4)
Cat. No.
ABIN2856855
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (3)
Cat. No.
ABIN530853
Quantity
50 μg
Datasheet
Datasheet
Recommended SESN3 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970191
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970190
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959451
Quantity
96 tests
Datasheet
Datasheet
Recommended SESN3 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1319667
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1319669
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7398665
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our SESN3 products
: "Autophagy mediators (FOXO1, SESN3 and TSC2) in Lewy body disease and aging." in: Neuroscience letters, Vol. 684, pp. 35-41, (2018) (PubMed).: "Reactive oxygen species induction by cabazitaxel through inhibiting Sestrin-3 in castration resistant prostate cancer." in: Oncotarget, Vol. 8, Issue 50, pp. 87675-87683, (2017) (PubMed).
: "Amino Acid-Induced Activation of mTORC1 in Rat Liver Is Attenuated by Short-Term Consumption of a High-Fat Diet." in: The Journal of nutrition, Vol. 145, Issue 11, pp. 2496-502, (2015) (PubMed).
: "GCN2 sustains mTORC1 suppression upon amino acid deprivation by inducing Sestrin2." in: Genes & development, Vol. 29, Issue 22, pp. 2331-6, (2015) (PubMed).
: "Regulatory effects of sestrin 3 (SESN3) in BCR-ABL expressing cells." in: PLoS ONE, Vol. 8, Issue 11, pp. e78780, (2013) (PubMed).
Synonyms and alternative names related to SESN3
sestrin 3 (SESN3), sestrin 3 (sesn3), sestrin 3 L homeolog (sesn3.L), sestrin 3 (Sesn3), 5630400E15Rik, BC003348, cb261, sb:cb261, sest3, SEST3, sestrin-3, wu:fb77c04, wu:fc41d03, wu:fd59d12, zgc:56722Protein level used designations for SESN3
- sestrin-3
- sestrin 3
- sestrin-3-like
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