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SESN1 Products

(Sestrin 1 (SESN1))

Categories

This gene encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The encoded protein mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010].

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Featured SESN1 Categories

SESN1 Antibodies

High quality antibodies with extensive validation data.

SESN1 ELISA Kits

Reliable ELISA kits for a wide range of species.

SESN1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SESN1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF
Validations
  • (1)
  • (3)
Cat. No. ABIN525920
Quantity 50 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, FACS
Validations
  • (3)
Cat. No. ABIN391992
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (3)
Cat. No. ABIN7270259
Quantity 100 μL
Datasheet Datasheet

Recommended SESN1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970186
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970187
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959448
Quantity 96 tests
Datasheet Datasheet

Recommended SESN1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1319663
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7398668
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3076724
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our SESN1 products

Ye, Palm, Peng, King, Lindsten, Li, Koumenis, Thompson: "GCN2 sustains mTORC1 suppression upon amino acid deprivation by inducing Sestrin2." in: Genes & development, Vol. 29, Issue 22, pp. 2331-6, (2015) (PubMed).

Renna, Bento, Fleming, Menzies, Siddiqi, Ravikumar, Puri, Garcia-Arencibia, Sadiq, Corrochano, Carter, Brown, Acevedo-Arozena, Rubinsztein: "IGF-1 receptor antagonism inhibits autophagy." in: Human molecular genetics, Vol. 22, Issue 22, pp. 4528-44, (2013) (PubMed).

Synonyms and alternative names related to SESN1

sestrin 1 (SESN1), sestrin 1 (sesn1), sestrin 1 (Sesn1), sestrin 1 L homeolog (sesn1.L), 1110002G11Rik, AU044290, pa26, PA26, Pa26, SESN1, sesn1-A, sest1, SEST1, Sest1, sestrin-1, XPA26, zgc:91970

Protein level used designations for SESN1

  • sestrin 1
  • sestrin-1
  • nuclear factor XPA26-T2
  • p53 activated gene 26
  • p53 regulated PA26 nuclear protein
  • p53 regulated Pa26 nuclear protein
  • p53-regulated protein PA26
  • XPA26
  • sestrin 1,nuclear factor XPA26-T2
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