serum/glucocorticoid Regulated Kinase 1 Products
(serum/glucocorticoid Regulated Kinase 1 (SGK1))
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This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2009].
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Featured serum/glucocorticoid Regulated Kinase 1 Categories
serum/glucocorticoid Regulated Kinase 1 Antibodies
High quality antibodies with extensive validation data.
serum/glucocorticoid Regulated Kinase 1 ELISA Kits
Reliable ELISA kits for a wide range of species.
serum/glucocorticoid Regulated Kinase 1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended serum/glucocorticoid Regulated Kinase 1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (13)
Cat. No.
ABIN6256329
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IHC (p), RNAi
Validations
- (7)
Cat. No.
ABIN562849
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (2)
- (5)
Cat. No.
ABIN3021291
Quantity
100 μL
Datasheet
Datasheet
Recommended serum/glucocorticoid Regulated Kinase 1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6974962
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380327
Quantity
2 x 96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380136
Quantity
2 x 96 tests
Datasheet
Datasheet
Recommended serum/glucocorticoid Regulated Kinase 1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN667573
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1319817
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1319815
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our serum/glucocorticoid Regulated Kinase 1 products
: "The E3 ubiquitin ligase Siah1 regulates adrenal gland organization and aldosterone secretion." in: JCI insight, Vol. 2, Issue 23, (2019) (PubMed).: "SGK1 inhibits PM2.5-induced apoptosis and oxidative stress in human lung alveolar epithelial A549 cells." in: Biochemical and biophysical research communications, Vol. 496, Issue 4, pp. 1291-1295, (2018) (PubMed).
"Retracted: 'Anti-fibrotic actions of Ghrelin by inhibition of the NADPH oxidase-ROS signaling pathway' by Qian Wang, Xin Sui, Rui Chen, Peiyong Ma, Tao Ding, Dianjun Sui, and Ping Yang." in: Clinical and experimental pharmacology & physiology, Vol. 45, Issue 8, pp. 885, (2018) (PubMed).
: "Neuropsin Inactivation Has Protective Effects against Depressive-Like Behaviours and Memory Impairment Induced by Chronic Stress." in: PLoS genetics, Vol. 12, Issue 10, pp. e1006356, (2017) (PubMed).
: "Potassium supplementation inhibits IL-17A production induced by salt loading in human T lymphocytes via p38/MAPK-SGK1 pathway." in: Experimental and molecular pathology, Vol. 100, Issue 3, pp. 370-7, (2016) (PubMed).
: "Serum and glucocorticoid-regulated kinase 1 promotes vascular smooth muscle cell proliferation via regulation of β-catenin dynamics." in: Cellular signalling, Vol. 26, Issue 12, pp. 2765-72, (2014) (PubMed).
: "Neurotrophic effects of serum- and glucocorticoid-inducible kinase on adult murine mesencephalic dopamine neurons." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 33, pp. 11299-308, (2012) (PubMed).
: "Multiple translational isoforms give functional specificity to serum- and glucocorticoid-induced kinase 1." in: Molecular biology of the cell, Vol. 18, Issue 6, pp. 2072-80, (2007) (PubMed).
: "An amphipathic helix targets serum and glucocorticoid-induced kinase 1 to the endoplasmic reticulum-associated ubiquitin-conjugation machinery." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 30, pp. 11178-83, (2006) (PubMed).
: "PPARgamma activation enhances cell surface ENaCalpha via up-regulation of SGK1 in human collecting duct cells." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 17, Issue 13, pp. 1966-8, (2003) (PubMed).
Synonyms and alternative names related to serum/glucocorticoid Regulated Kinase 1
serum/glucocorticoid regulated kinase 1 (SGK1), serum/glucocorticoid regulated kinase 1 (Sgk1), Serine/threonine-protein kinase sgk-1 (sgk-1), serum/glucocorticoid regulated kinase 1 S homeolog (sgk1.S), serum/glucocorticoid regulated kinase 1 (sgk1), serum/glucocorticoid regulated kinase 1 L homeolog (sgk1.L), cb1083, SGK, Sgk, sgk, sgk-A, sgk-B, sgk1, sgk1-a, sgk1-b, sgk2, wu:fc20a09Protein level used designations for serum/glucocorticoid Regulated Kinase 1
- Sgk1 variant i3
- serine/threonine protein kinase SGK
- serine/threonine-protein kinase Sgk1
- serum/glucocorticoid-regulated kinase 1
- serum and glucocorticoid-dependent protein kinase
- serum/glucocorticoid regulatory kinase
- serum- and glucocorticoid-induced kinase
- serum and glucocorticoid-regulated protein kinase
- Serum/glucocorticoid-regulated kinase 1-B
- serine/threonine-protein kinase Sgk1-B
- serum/glucocorticoid regulated kinase 2
- Serum/glucocorticoid-regulated kinase 1-A
- serine/threonine-protein kinase Sgk1-A
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