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Serine Palmitoyltransferase, Small Subunit B (SPTSSB) protein (Myc-DYKDDDDK Tag)

SPTSSB Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2714119
  • Target See all Serine Palmitoyltransferase, Small Subunit B (SPTSSB) products
    Serine Palmitoyltransferase, Small Subunit B (SPTSSB)
    Protein Type
    Recombinant
    Origin
    Human
    Source
    HEK-293 Cells
    Purification tag / Conjugate
    Myc-DYKDDDDK Tag
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Chromosome 3 open reading frame 57 (C3orf57) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    Serine Palmitoyltransferase, Small Subunit B (SPTSSB)
    Alternative Name
    Chromosome 3 Open Reading Frame 57 (c3orf57)
    Synonyms
    C1H3orf57 Protein, C3orf57 Protein, ADMP Protein, SSSPTB Protein, 1110032A04Rik Protein, Sssptb Protein, admp Protein, sssptb Protein, serine palmitoyltransferase small subunit B Protein, serine palmitoyltransferase, small subunit B Protein, serine palmitoyltransferase small subunit B L homeolog Protein, SPTSSB Protein, Sptssb Protein, sptssb.L Protein
    Background
    Serine palmitoyltransferase (SPT EC 2.3.1.50) catalyzes the first committed and rate-limiting step in sphingolipid biosynthesis. SSSPTB is a small SPT subunit that stimulates SPT activity and confers acyl-CoA preference to the SPT catalytic heterodimer of SPTLC1 (MIM 605712) and either SPTLC2 (MIM 605713) or SPTLC3 (MIM 611120) (Han et al., 2009 [PubMed 19416851]).[supplied by OMIM, Nov 2010].
    Molecular Weight
    9 kDa
    NCBI Accession
    NP_001035189
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