SEPHS2 Products
(Selenophosphate Synthetase 2 (SEPHS2))
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This gene encodes an enzyme that synthesizes selenophosphate from selenide and ATP. Selenophosphate is the selenium donor used to synthesize selenocysteine, which is co-translationally incorporated into selenoproteins at in-frame UGA codons. This protein itself contains a selenocysteine residue in its predicted active site. The 3' UTR of the gene has a stem-loop secondary structure called a selenocysteine insertion sequence (SECIS) element, which allows UGA to direct the incorporation of selenocysteine rather than signal a translational stop. Alternatively spliced transcripts have been identified, but their biological validity has not been determined. [provided by RefSeq, Jul 2008].
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Featured SEPHS2 Categories
SEPHS2 Antibodies
High quality antibodies with extensive validation data.
SEPHS2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SEPHS2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (4)
Cat. No.
ABIN564961
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), ICC, IF
Validations
- (3)
Cat. No.
ABIN2855698
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN233801
Quantity
100 μg
Datasheet
Datasheet
Recommended SEPHS2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1319524
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1319526
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2731660
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our SEPHS2 products
: "Competition between the Brain and Testes under Selenium-Compromised Conditions: Insight into Sex Differences in Selenium Metabolism and Risk of Neurodevelopmental Disease." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 46, pp. 15326-38, (2015) (PubMed).: "Selenophosphate synthetase genes from lung adenocarcinoma cells: Sps1 for recycling L-selenocysteine and Sps2 for selenite assimilation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 46, pp. 16162-7, (2004) (PubMed).
: "Fetal mouse selenophosphate synthetase 2 (SPS2): biological activities of mutant forms in Escherichia coli." in: Molecules and cells, Vol. 9, Issue 4, pp. 422-8, (2000) (PubMed).
: "Novel selenoproteins identified in silico and in vivo by using a conserved RNA structural motif." in: The Journal of biological chemistry, Vol. 274, Issue 53, pp. 38147-54, (2000) (PubMed).
: "Cell cycle control in mammalian cells: role of cyclins, cyclin dependent kinases (CDKs), growth suppressor genes and cyclin-dependent kinase inhibitors (CKIs)." in: Oncogene, Vol. 11, Issue 2, pp. 211-9, (1995) (PubMed).
Synonyms and alternative names related to SEPHS2
Selenophosphate synthetase 2 (Sps2), selenophosphate synthetase 2 (sephs2), selenophosphate synthetase 2 (SEPHS2), selenophosphate synthetase 2 L homeolog (sephs2.L), selenophosphate synthetase 2 (Sephs2), cb701, CG5025, Dmel\\CG5025, Dsps2, dSPS2, dsps2, MGC145309, SEPHS2, sephs2, sps, SPS2, sps2, Sps2, SPS2b, Ysg3, zgc:92096Protein level used designations for SEPHS2
- CG5025-PA
- CG5025-PB
- CG5025-PC
- CG5025-PD
- Sps2-PA
- Sps2-PB
- Sps2-PC
- Sps2-PD
- selenophosphate synthetase 2
- selenide, water dikinase 2
- clone 1000
- selenium donor protein 2
- selenophosphate synthase 2
- the SelD gene product
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