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Separase Antibodies

(Extra Spindle Poles Like 1 (ESPL1))

Your search for reliable Separase antibodies ends here. Separase, known by aliases such as ESPL1, espl1, Espl1, is an integral part of our antibody range. Whether you're working with Human, Mouse, Rat, or other species, our range of Separase antibodies offer precise detection across diverse samples. These specialized antibodies are tailored for various scientific applications like ELISA, IHC, IF (cc), IF (p), WB, providing you with options like polyclonal, recombinant, and monoclonal antibodies, sourced from different host species such as Rabbit, Mouse, Goat. The efficacy of our antibodies is well-established, demonstrated through multiple methods.

Detailed information, including references, images, and validations by other customers, can be found on each product page. Should you require assistance in finding a specific product, our customer service team is ready to assist. Utilize our Separase antibodies in your research endeavors for dependable Separase detection.

Separase antibody  (AA 586-701) Separase antibody  (AA 586-701) Separase antibody (AA 586-701) (ABIN564183)

ESPL1 Reactivity: Human ELISA, WB, IHC (p) Host: Mouse Monoclonal 6H6 unconjugated

Separase antibody  (pSer1126) Separase antibody  (pSer1126) Separase antibody (pSer1126) (ABIN389654)

ESPL1 Reactivity: Human IHC (p), DB Host: Rabbit Polyclonal RB7943 unconjugated

Separase antibody Separase antibody Separase antibody (ABIN7238939)

ESPL1 Reactivity: Human, Mouse ELISA, IHC, WB Host: Rabbit Polyclonal unconjugated

Separase Antibodies by Reactivity

Find Separase Antibodies for a variety of species such as anti-Human Separase, anti-Mouse Separase, anti-Rat Separase. The species listed below are among those available. Click on a link to go to the corresponding products.

Separase Antibodies by Application

Find Separase Antibodies validated for a specific application such as ELISA, IHC, IF (cc), IF (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

Separase Antibodies by Host

Find Separase Antibodies with a specific Host. The Host listed below are among those available. Click on a link to go to the corresponding products.

Separase Antibodies by Binding Specificity

Find Separase Antibodies with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

Separase Antibodies by Clonality

Find available monoclonal or polyclonal Separase Antibodies. Click on a link to go to the corresponding products.

Separase Antibodies by Clone

Find Separase Antibodies with a specific Clone. The Clone listed below are among those available. Click on a link to go to the corresponding products.

Separase Antibodies by Conjugate

Find Separase Antibodies with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular Separase Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, WB, IHC (p)
Validations
  • (7)
  • (3)
Cat. No. ABIN564183
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IHC (p), DB
Validations
  • (1)
  • (2)
Cat. No. ABIN389654
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, IHC, WB
Validations
  • (3)
Cat. No. ABIN7238939
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, IHC, WB, IF
Validations
  • (2)
Cat. No. ABIN3186905
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, IHC, WB, IF
Validations
  • (3)
Cat. No. ABIN1532260
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, WB, IF, IC
Validations
  • (3)
Cat. No. ABIN7299556
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, WB, IF
Validations
  • (1)
Cat. No. ABIN7182656
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IF
Validations
  • (1)
Cat. No. ABIN7168853
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, IHC, WB, IF
Validations
  • (1)
Cat. No. ABIN3182749
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB
Validations
  • (1)
Cat. No. ABIN6254173
Quantity 800 μg
Datasheet Datasheet
Reactivity Human
Application IF
Validations
  • (1)
Cat. No. ABIN7265212
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (1)
Cat. No. ABIN7267070
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC (p), EIA
Validations
  • (2)
Cat. No. ABIN358223
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, IHC, WB, IF
Validations
  • (2)
Cat. No. ABIN6284992
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7168856
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our Separase Antibodies

Mukherjee, Ge, Zhang, Edwards, Sumazin, Sharan, Rao, Medina, Pati: "MMTV-Espl1 transgenic mice develop aneuploid, estrogen receptor alpha (ER?)-positive mammary adenocarcinomas." in: Oncogene, Vol. 33, Issue 48, pp. 5511-22, (2014) (PubMed).

Mukherjee, Byrd, Brawley, Bielamowicz, Li, Merchant, Maitra, Sumazin, Fuller, Kew, Sun, Powell, Ahmed, Zhang, Pati: "Overexpression and constitutive nuclear localization of cohesin protease Separase protein correlates with high incidence of relapse and reduced overall survival in glioblastoma multiforme." in: Journal of neuro-oncology, Vol. 119, Issue 1, pp. 27-35, (2014) (PubMed).

Zhang, Scorsone, Ge, Kaffes, Dobrolecki, Mukherjee, Lewis, Berg, Stephan, Pati: "Identification and Characterization of Separase Inhibitors (Sepins) for Cancer Therapy." in: Journal of biomolecular screening, Vol. 19, Issue 6, pp. 878-889, (2014) (PubMed).

Haaß, Stehle, Nittka, Giehl, Schrotz-King, Fabarius, Hofmann, Seifarth: "The proteolytic activity of separase in BCR-ABL-positive cells is increased by imatinib." in: PLoS ONE, Vol. 7, Issue 8, pp. e42863, (2012) (PubMed).

Mukherjee, Ge, Zhang, Huang, Nakamura, Minor, Fofanov, Rao, Herron, Pati: "Separase loss of function cooperates with the loss of p53 in the initiation and progression of T- and B-cell lymphoma, leukemia and aneuploidy in mice." in: PLoS ONE, Vol. 6, Issue 7, pp. e22167, (2011) (PubMed).

Panigrahi, Zhang, Mao, Pati: "Calpain-1 cleaves Rad21 to promote sister chromatid separation." in: Molecular and cellular biology, Vol. 31, Issue 21, pp. 4335-47, (2011) (PubMed).

Meyer, Fofanov, Panigrahi, Merchant, Zhang, Pati: "Overexpression and mislocalization of the chromosomal segregation protein separase in multiple human cancers." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 15, Issue 8, pp. 2703-10, (2009) (PubMed).

Kim, Jeon, Ha, Park, Kim, Shin, Lee, Chung, Lee: "Functional interaction between BubR1 and securin in an anaphase-promoting complex/cyclosomeCdc20-independent manner." in: Cancer research, Vol. 69, Issue 1, pp. 27-36, (2009) (PubMed).

Sun, Kucej, Fan, Yu, Sun, Zou: "Separase is recruited to mitotic chromosomes to dissolve sister chromatid cohesion in a DNA-dependent manner." in: Cell, Vol. 137, Issue 1, pp. 123-32, (2009) (PubMed).

Fujita, Epperly, Zou, Greenberger, Wan: "Regulation of the anaphase-promoting complex-separase cascade by transforming growth factor-beta modulates mitotic progression in bone marrow stromal cells." in: Molecular biology of the cell, Vol. 19, Issue 12, pp. 5446-55, (2008) (PubMed).

Aliases for Separase Antibodies

extra spindle pole bodies like 1, separase (ESPL1) Antibodies
extra spindle poles like 1 (espl1) Antibodies
extra spindle pole bodies 1, separase (Espl1) Antibodies
extra spindle pole bodies like 1, separase (Espl1) Antibodies
AL024103 Antibodies
AU045071 Antibodies
Cerp Antibodies
ESP1 Antibodies
mp:zf637-3-001691 Antibodies
PRCE Antibodies
SEPA Antibodies
SSE Antibodies
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