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SEMA6D Products

(Sema Domain, Transmembrane Domain (TM), and Cytoplasmic Domain, (Semaphorin) 6D (SEMA6D))

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Semaphorins are a large family, including both secreted and membrane associated proteins, many of which have been implicated as inhibitors or chemorepellents in axon pathfinding, fasciculation and branching, and target selection. All semaphorins possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Additional sequence motifs C-terminal to the semaphorin domain allow classification into distinct subfamilies. Results demonstrate that transmembrane semaphorins, like the secreted ones, can act as repulsive axon guidance cues. This gene encodes a class 6 vertebrate transmembrane semaphorin that demonstrates alternative splicing. Several transcript variants have been identified and expression of the distinct encoded isoforms is thought to be regulated in a tissue- and development-dependent manner. [provided by RefSeq, Nov 2010].

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Featured SEMA6D Categories

SEMA6D Antibodies

High quality antibodies with extensive validation data.

SEMA6D Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SEMA6D Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB
Validations
  • (1)
  • (4)
Cat. No. ABIN2783810
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (3)
Cat. No. ABIN529177
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (2)
Cat. No. ABIN7168827
Quantity 100 μg
Datasheet Datasheet

Recommended SEMA6D ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4884465
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6386236
Quantity 96 tests
Datasheet Datasheet

Recommended SEMA6D Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1319498
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
Cat. No. ABIN1319497
Quantity 25 μg
Datasheet Datasheet

Latest Publications for our SEMA6D products

Mortusewicz, Evers, Helleday: "PC4 promotes genome stability and DNA repair through binding of ssDNA at DNA damage sites." in: Oncogene, (2015) (PubMed).

Toyofuku, Zhang, Kumanogoh, Takegahara, Suto, Kamei, Aoki, Yabuki, Hori, Fujisawa, Kikutani: "Dual roles of Sema6D in cardiac morphogenesis through region-specific association of its receptor, Plexin-A1, with off-track and vascular endothelial growth factor receptor type 2." in: Genes & development, Vol. 18, Issue 4, pp. 435-47, (2004) (PubMed).

Synonyms and alternative names related to SEMA6D

semaphorin 6D (SEMA6D), sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D (Sema6d), semaphorin 6D (Sema6d), sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D (SEMA6D), sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D (sema6d), semaphorin 6D L homeolog (sema6d.L), 1110067B02Rik, AA409156, D330011G23, mKIAA1479, Sema6D-1, Sema6D-2, Sema6D-4, Sema6D-5, Sema6D-6, wu:fi06a12, wu:fi76a10, zgc:56170

Protein level used designations for SEMA6D

  • semaphorin-6D
  • semaphorin 6D
  • semaphorin-6C
  • semaphorin 6D4
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