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SEMA3F Products

(Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3F (SEMA3F))
The semaphorins are a family of proteins that are involved in signaling. All the family members have a secretion signal, a 500-amino acid sema domain, and 16 conserved cysteine residues (Kolodkin et al., 1993 [PubMed 8269517]). Sequence comparisons have grouped the secreted semaphorins into 3 general classes, all of which also have an immunoglobulin domain. The semaphorin III family, consisting of human semaphorin III (SEMA3A\; MIM 603961), chicken collapsin, and mouse semaphorins A, D, and E, all have a basic domain at the C terminus. Chicken collapsin contributes to path finding by axons during development by inhibiting extension of growth cones (Luo et al., 1993 [PubMed 8402908]) through an interaction with a collapsin response mediator protein of relative molecular mass 62K (CRMP62) (Goshima et al., 1995 [PubMed 7637782]), a putative homolog of an axonal guidance associated UNC33 gene product (MIM 601168). SEMA3F is a secreted member of the semaphorin III family.[supplied by OMIM, Mar 2008].

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Featured SEMA3F Categories

SEMA3F Antibodies

High quality antibodies with extensive validation data.

SEMA3F ELISA Kits

Reliable ELISA kits for a wide range of species.

SEMA3F Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SEMA3F Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IF (p), IF (cc), ICC, IHC (fro), IHC (p)
Validations
  • (4)
Cat. No. ABIN737976
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB, IHC, IP
Validations
  • (3)
Cat. No. ABIN2786778
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (1)
Cat. No. ABIN7168793
Quantity 100 μg
Datasheet Datasheet

Recommended SEMA3F ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN6959351
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959352
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6951718
Quantity 96 tests
Datasheet Datasheet

Recommended SEMA3F Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7403633
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7386185
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3011609
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our SEMA3F products

Plant, Eamsamarng, Sanchez-Garcia, Reyes, Renshaw, Coelho, Mirchandani, Morgan, Ellett, Morrison, Humphries, Watts, Murphy, Raffo-Iraolagoitia, Zhang, Cash, Loynes, Elks, Van Eeden, Carlin, Furley et al.: "Semaphorin 3F signaling actively retains neutrophils at sites of inflammation. ..." in: The Journal of clinical investigation, Vol. 130, Issue 6, pp. 3221-3237, (2020) (PubMed).

Stallone, Matteo, Netti, Infante, Di Lorenzo, Prattichizzo, Carlucci, Trezza, Gesualdo, Greco, Grandaliano: "Semaphorin 3F expression is reduced in pregnancy complicated by preeclampsia. An observational clinical study." in: PLoS ONE, Vol. 12, Issue 3, pp. e0174400, (2017) (PubMed).

Scheerer, Frangini, Chiantera, Mechsner: "Reduced Sympathetic Innervation in Endometriosis is Associated to Semaphorin 3C and 3F Expression." in: Molecular neurobiology, Vol. 54, Issue 7, pp. 5131-5141, (2016) (PubMed).

Bollard, Massoma, Vercherat, Blanc, Lepinasse, Gadot, Couderc, Poncet, Walter, Joly, Hervieu, Scoazec, Roche: "The axon guidance molecule semaphorin 3F is a negative regulator of tumor progression and proliferation in ileal neuroendocrine tumors." in: Oncotarget, Vol. 6, Issue 34, pp. 36731-45, (2015) (PubMed).

Masiero, Simões, Han, Snell, Peterkin, Bridges, Mangala, Wu, Pradeep, Li, Han, Dalton, Lopez-Berestein, Tuynman, Mortensen, Li, Patient, Sood, Banham, Harris, Buffa: "A core human primary tumor angiogenesis signature identifies the endothelial orphan receptor ELTD1 as a key regulator of angiogenesis." in: Cancer cell, Vol. 24, Issue 2, pp. 229-41, (2013) (PubMed).

Favier, Alam, Barron, Bonnin, Laboudie, Fons, Mandron, Herault, Neufeld, Savi, Herbert, Bono: "Neuropilin-2 interacts with VEGFR-2 and VEGFR-3 and promotes human endothelial cell survival and migration." in: Blood, Vol. 108, Issue 4, pp. 1243-50, (2006) (PubMed).

Synonyms and alternative names related to SEMA3F

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F (Sema3f), semaphorin 3F (Sema3f), semaphorin 3F (SEMA3F), semaphorin 3F (sema3f), semaphorin 3F L homeolog (sema3f.L), sema-iv, SEMA-IV, SEMA3F, Sema4, sema4, SEMA4, SemaIV, Semak, semak, SEMAK, semaphorin-3F

Protein level used designations for SEMA3F

  • semaphorin IV
  • semaphorin-3F
  • semaphorin 3F
  • sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
  • sema iv
  • sema III/F
  • sema IV
  • sema domain, immunoglobulin domain (Ig), short basic domain, secreted, 3F
  • semaphorin III/F
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