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Seladin 1 Products

(24-Dehydrocholesterol Reductase (DHCR24))

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This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells. [provided by RefSeq, Jul 2008].

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Featured Seladin 1 Categories

Seladin 1 Antibodies

High quality antibodies with extensive validation data.

Seladin 1 ELISA Kits

Reliable ELISA kits for a wide range of species.

Seladin 1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Seladin 1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC (p), IF, ICC
Validations
  • (5)
Cat. No. ABIN2855685
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (3)
Cat. No. ABIN7149658
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC
Validations
  • (2)
Cat. No. ABIN6264970
Quantity 100 μL
Datasheet Datasheet

Recommended Seladin 1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6953352
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Sandwich ELISA
Validations
Cat. No. ABIN420800
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1129411
Quantity 96 tests
Datasheet Datasheet

Recommended Seladin 1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1351528
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2731608
Quantity 20 μg
Datasheet Datasheet
Reactivity Rat
Source Yeast
Validations
Cat. No. ABIN1632998
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our Seladin 1 products

Gilk, Cockrell, Luterbach, Hansen, Knodler, Ibarra, Steele-Mortimer, Heinzen: "Bacterial colonization of host cells in the absence of cholesterol." in: PLoS pathogens, Vol. 9, Issue 1, pp. e1003107, (2013) (PubMed).

Gilk, Beare, Heinzen: "Coxiella burnetii expresses a functional Δ24 sterol reductase." in: Journal of bacteriology, Vol. 192, Issue 23, pp. 6154-9, (2010) (PubMed).

Synonyms and alternative names related to Seladin 1

24-dehydrocholesterol reductase (DHCR24), 24-dehydrocholesterol reductase S homeolog (dhcr24.S), 24-dehydrocholesterol reductase (dhcr24), delta(24)-sterol reductase (LOC5575872), 24-dehydrocholesterol reductase (CpipJ_CPIJ000670), 24-dehydrocholesterol reductase (Dhcr24), 2310076D10Rik, 5830417J06Rik, DCE, MGC82737, mKIAA0018, Nbla03646, seladin-1, SELADIN1, zgc:101638

Protein level used designations for Seladin 1

  • 24-dehydrocholesterol reductase
  • 3 beta-hydroxysterol delta 24-reductase
  • 3-beta-hydroxysterol delta-24-reductase
  • delta(24)-sterol reductase
  • desmosterol-to-cholesterol enzyme
  • diminuto/dwarf1 homolog
  • seladin 1
  • selective AD indicator 1
  • 3-beta-hydroxysterol delta-24 reductase
  • seladin-1
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