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Secretory Component Products

(Secretory Component)

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This gene is a member of the immunoglobulin superfamily. The encoded poly-Ig receptor binds polymeric immunoglobulin molecules at the basolateral surface of epithelial cells\; the complex is then transported across the cell to be secreted at the apical surface. A significant association was found between immunoglobulin A nephropathy and several SNPs in this gene.[provided by RefSeq, Sep 2009].

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Recommended Secretory Component Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, WB, IF, H
Validations
  • (1)
Cat. No. ABIN457936
Quantity 0.5 mg
Datasheet Datasheet
Reactivity Human
Application IEP
Validations
  • (2)
Cat. No. ABIN457970
Quantity 1 mL
Datasheet Datasheet
Reactivity Monkey
Application IEP
Validations
  • (1)
Cat. No. ABIN458282
Quantity 1 mL
Datasheet Datasheet

Recommended Secretory Component ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6973884
Quantity 96 tests
Datasheet Datasheet

Recommended Secretory Component Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
Cat. No. ABIN7013229
Quantity 200 μg
Datasheet Datasheet

Latest Publications for our Secretory Component products

Roos Ljungberg, Joshua, Skogh, Eklund, Sköld, Karimi, Nyrén, Svärd, Catrina, Kastbom: "Secretory anti-citrullinated protein antibodies in serum associate with lung involvement in early rheumatoid arthritis." in: Rheumatology (Oxford, England), Vol. 59, Issue 4, pp. 852-859, (2020) (PubMed).

Roos, Martinsson, Ziegelasch, Sommarin, Svärd, Skogh, Kastbom: "Circulating secretory IgA antibodies against cyclic citrullinated peptides in early rheumatoid arthritis associate with inflammatory activity and smoking." in: Arthritis research & therapy, Vol. 18, Issue 1, pp. 119, (2017) (PubMed).

Thomas, Tuero, Demberg, Vargas-Inchaustegui, Musich, Xiao, Venzon, LaBranche, Montefiori, DiPasquale, Reed, DeVico, Fouts, Lewis, Gallo, Robert-Guroff: "HIV-1 CD4-induced (CD4i) gp120 epitope vaccines promote B and T-cell responses that contribute to reduced viral loads in rhesus macaques." in: Virology, Vol. 471-473, pp. 81-92, (2015) (PubMed).

Fry, Sinclair, Timms, Leathem, Dwek: "A targeted glycoproteomic approach identifies cadherin-5 as a novel biomarker of metastatic breast cancer." in: Cancer letters, Vol. 328, Issue 2, pp. 335-44, (2012) (PubMed).

Synonyms and alternative names related to Secretory Component

polymeric immunoglobulin receptor (PIGR), polymeric immunoglobulin receptor (Pigr), pIgA-R, RNPIGR2

Protein level used designations for Secretory Component

  • hepatocellular carcinoma associated protein TB6
  • hepatocellular carcinoma-associated protein TB6
  • poly-Ig receptor
  • phosphatidylinositol glycan, class R
  • polymeric IgA receptor
  • poly-IG receptor
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