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Sec8 Products

(Exocyst Complex Component 4 (EXOC4))

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The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].

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Featured Sec8 Categories

Sec8 Antibodies

High quality antibodies with extensive validation data.

Sec8 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Sec8 Antibodies

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Reactivity Human
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Cat. No. ABIN6242316
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Cat. No. ABIN6744025
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Quantity 10 μg
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Cat. No. ABIN2720613
Quantity 50 μg
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Latest Publications for our Sec8 products

Liu, Qi, Li, Hsu, Saadat, Hsu, Rahimi, Lee, Yan, Tian, Han: "CREG1 Interacts with Sec8 to Promote Cardiomyogenic Differentiation and Cell-Cell Adhesion." in: Stem cells (Dayton, Ohio), (2016) (PubMed).

Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).

Imai, Yoshie, Haga-Tsujimura, Nashida, Shimomura: "Exocyst subunits are involved in isoproterenol-induced amylase release from rat parotid acinar cells." in: European journal of oral sciences, Vol. 120, Issue 2, pp. 123-31, (2012) (PubMed).

Charron, Nakamura, Bacallao, Wandinger-Ness: "Compromised cytoarchitecture and polarized trafficking in autosomal dominant polycystic kidney disease cells." in: The Journal of cell biology, Vol. 149, Issue 1, pp. 111-24, (2000) (PubMed).

Duncan, Don-Wauchope, Tapechum, Shipston, Chow, Estibeiro: "High-efficiency Semliki Forest virus-mediated transduction in bovine adrenal chromaffin cells." in: The Biochemical journal, Vol. 342 Pt 3, pp. 497-501, (1999) (PubMed).

Hazuka, Hsu, Scheller: "Characterization of a cDNA encoding a subunit of the rat brain rsec6/8 complex." in: Gene, Vol. 187, Issue 1, pp. 67-73, (1997) (PubMed).

Ting, Hazuka, Hsu, Kirk, Bean, Scheller: "rSec6 and rSec8, mammalian homologs of yeast proteins essential for secretion." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, Issue 21, pp. 9613-7, (1995) (PubMed).

Synonyms and alternative names related to Sec8

Secretory 8 (Sec8), exocyst complex component 4 (EXOC4), exocyst complex component 4 (CpipJ_CPIJ001354), exocyst complex component 4 (Exoc4), exocyst complex component 4 (exoc4), exocyst complex component 4 L homeolog (exoc4.L), Exocyst complex component 4 (sec-8), subunit of exocyst complex 8 (SEC8), ALR, ATSEC8, C78892, CG2095, DKFZp459N1430, Dmel\\CG2095, dsec8, fun, Sec8, SEC8, SEC8L1, Sec8l1, Sec8p, si:ch211-92l17.2, si:rp71-18a24.2, SUBUNIT OF EXOCYST COMPLEX 8, subunit of exocyst complex 8

Protein level used designations for Sec8

  • CG2095-PA
  • funnel cakes
  • sec8-PA
  • SEC8 protein
  • exocyst complex component 4
  • SEC8-like 1
  • exocyst complex component Sec8
  • augmenter of liver regeneration (ALR) pseudogene
  • rSec8
  • secretory protein SEC8
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