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SEC62 Products

(Translocation Protein 1 (TLOC1))
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER. [provided by RefSeq, Jul 2008].

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Featured SEC62 Categories

SEC62 Antibodies

High quality antibodies with extensive validation data.

SEC62 ELISA Kits

Reliable ELISA kits for a wide range of species.

SEC62 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SEC62 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
Cat. No. ABIN656777
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p), IF, EIA
Validations
  • (2)
Cat. No. ABIN1450053
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), EIA
Validations
  • (2)
Cat. No. ABIN954706
Quantity 0.4 mL
Datasheet Datasheet

Recommended SEC62 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1162850
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1162851
Quantity 96 tests
Datasheet Datasheet
Reactivity Dog
Analytical Method
Validations
Cat. No. ABIN1162848
Quantity 96 tests
Datasheet Datasheet

Recommended SEC62 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3105724
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3125261
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2731581
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our SEC62 products

Chino, Hatta, Natsume, Mizushima: "Intrinsically Disordered Protein TEX264 Mediates ER-phagy." in: Molecular cell, Vol. 74, Issue 5, pp. 909-921.e6, (2019) (PubMed).

Jadhav, McKenna, Johnson, High, Sinning, Pool: "Mammalian SRP receptor switches the Sec61 translocase from Sec62 to SRP-dependent translocation." in: Nature communications, Vol. 6, pp. 10133, (2015) (PubMed).

Hagerstrand, Tong, Schumacher, Ilic, Shen, Cheung, Vazquez, Shrestha, Kim, Giacomelli, Rosenbluh, Schinzel, Spardy, Barbie, Mermel, Weir, Garraway, Tamayo, Mesirov, Beroukhim, Hahn: "Systematic interrogation of 3q26 identifies TLOC1 and SKIL as cancer drivers." in: Cancer discovery, Vol. 3, Issue 9, pp. 1044-57, (2013) (PubMed).

Lakkaraju, Thankappan, Mary, Garrison, Taunton, Strub: "Efficient secretion of small proteins in mammalian cells relies on Sec62-dependent posttranslational translocation." in: Molecular biology of the cell, Vol. 23, Issue 14, pp. 2712-22, (2012) (PubMed).

Synonyms and alternative names related to SEC62

SEC62 homolog, preprotein translocation factor S homeolog (sec62.S), SEC62 homolog, preprotein translocation factor (SEC62), SEC62 homolog, preprotein translocation factor (sec62), membrane unit of ER protein translocation apparatus (SEC62), SEC62 homolog (S. cerevisiae) (Sec62), SEC62 homolog, preprotein translocation factor (Sec62), 3100002M17Rik, Ab2-292, AI844545, AW545092, Dtrp1, HTP1, tloc1, TLOC1, Tloc1, TP-1, wu:fb57b06, zgc:114073

Protein level used designations for SEC62

  • translocation protein 1
  • translocation protein SEC62
  • fb57b06
  • uncharacterized protein LOC696989
  • hypothetical protein
  • hTP-1
  • membrane protein SEC62, S.cerevisiae, homolog of
  • TP-1
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