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SDHC Products

(Succinate Dehydrogenase Complex, Subunit C, Integral Membrane Protein, 15kDa (SDHC))
This gene encodes one of four nuclear-encoded subunits that comprise succinate dehydrogenase, also known as mitochondrial complex II, a key enzyme complex of the tricarboxylic acid cycle and aerobic respiratory chains of mitochondria. The encoded protein is one of two integral membrane proteins that anchor other subunits of the complex, which form the catalytic core, to the inner mitochondrial membrane. Several related pseudogenes are located in different genomic regions. Mutations in this gene have been associated with paragangliomas. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].

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Featured SDHC Categories

SDHC Antibodies

High quality antibodies with extensive validation data.

SDHC ELISA Kits

Reliable ELISA kits for a wide range of species.

SDHC Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

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Latest Publications for our SDHC products

Yan, Zhang, Jiao, Wang, He, Zhang, Zhang, Lv, Peng, Cai, Tian: "Quantitative proteomics in A30P*A53T α-synuclein transgenic mice reveals upregulation of Sel1l." in: PLoS ONE, Vol. 12, Issue 8, pp. e0182092, (2017) (PubMed).

Lemarie, Huc, Pazarentzos, Mahul-Mellier, Grimm: "Specific disintegration of complex II succinate:ubiquinone oxidoreductase links pH changes to oxidative stress for apoptosis induction." in: Cell death and differentiation, Vol. 18, Issue 2, pp. 338-49, (2011) (PubMed).

Lemarie, Grimm: "Mutations in the heme b-binding residue of SDHC inhibit assembly of respiratory chain complex II in mammalian cells." in: Mitochondrion, Vol. 9, Issue 4, pp. 254-60, (2009) (PubMed).

Synonyms and alternative names related to SDHC

succinate dehydrogenase complex subunit C (SDHC), succinate dehydrogenase complex subunit C (sdhc), succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa (SdhC), succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa (SDHC), succinate dehydrogenase complex, subunit C, integral membrane protein (Sdhc), succinate dehydrogenase complex subunit C (Sdhc), 0610010E03Rik, AI316496, AU019277, CYB560, CYBL, PGL3, QPS1, SDH3, SDHC

Protein level used designations for SDHC

  • succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa
  • ENSANGP00000017418-like protein
  • OXPHOS complex II cytochrome B560 subunit
  • succinate dehydrogenase C
  • succinate dehydrogenase cytochrome b560 subunit, mitochondrial
  • QPs-1
  • QPs1
  • integral membrane protein CII-3
  • succinate dehydrogenase complex, subunit C
  • cytochrome B large subunit of complex II
  • integral membrane protein CII-3b
  • succinate dehydrgenase cytochrome b
  • succinate dehydrogenase 3, integral membrane subunit
  • succinate-ubiquinone oxidoreductase cytochrome B large subunit
  • succinate dehydrogenase complex subunit C
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