SDHB Products
(Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB))
Categories
Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis. [provided by RefSeq, Jul 2008].
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Featured SDHB Categories
SDHB Antibodies
High quality antibodies with extensive validation data.
SDHB ELISA Kits
Reliable ELISA kits for a wide range of species.
SDHB Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SDHB Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (8)
Cat. No.
ABIN7441589
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC
Validations
- (6)
Cat. No.
ABIN7255423
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, FACS
Validations
- (5)
Cat. No.
ABIN7193552
Quantity
100 μL
Datasheet
Datasheet
Recommended SDHB ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959732
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959733
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5674884
Quantity
96 tests
Datasheet
Datasheet
Recommended SDHB Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1319365
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7424749
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7409461
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our SDHB products
: "Genetic identification of thiosulfate sulfurtransferase as an adipocyte-expressed antidiabetic target in mice selected for leanness. ..." in: Nature medicine, Vol. 22, Issue 7, pp. 771-9, (2016) (PubMed).: "The effect of 3-bromopyruvate on human colorectal cancer cells is dependent on glucose concentration but not hexokinase II expression." in: Bioscience reports, Vol. 36, Issue 1, pp. e00299, (2016) (PubMed).
: "Stable nuclear expression of ATP8 and ATP6 genes rescues a mtDNA Complex V null mutant." in: Nucleic acids research, Vol. 44, Issue 19, pp. 9342-9357, (2016) (PubMed).
: "SDHB/SDHA immunohistochemistry in pheochromocytomas and paragangliomas: a multicenter interobserver variation analysis using virtual microscopy: a Multinational Study of the European Network for the ..." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 28, Issue 6, pp. 807-21, (2015) (PubMed).
: "C11orf83, a mitochondrial cardiolipin-binding protein involved in bc1 complex assembly and supercomplex stabilization." in: Molecular and cellular biology, Vol. 35, Issue 7, pp. 1139-56, (2015) (PubMed).
: "APOBEC3A cytidine deaminase induces RNA editing in monocytes and macrophages." in: Nature communications, Vol. 6, pp. 6881, (2015) (PubMed).
: "A MEN1 syndrome with a paraganglioma." in: European journal of human genetics : EJHG, Vol. 22, Issue 2, pp. 283-5, (2014) (PubMed).
: "Integrated genomic study of quadruple-WT GIST (KIT/PDGFRA/SDH/RAS pathway wild-type GIST)." in: BMC cancer, Vol. 14, pp. 685, (2014) (PubMed).
: "Paraganglioma and pheochromocytoma upon maternal transmission of SDHD mutations." in: BMC medical genetics, Vol. 15, pp. 111, (2014) (PubMed).
: "Tyrosine kinase receptors as molecular targets in pheochromocytomas and paragangliomas." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 27, Issue 8, pp. 1050-62, (2014) (PubMed).
Synonyms and alternative names related to SDHB
succinate dehydrogenase complex iron sulfur subunit B (SDHB), succinate dehydrogenase [ubiquinone] iron-sulfur subunit 3 (SDH2-3), Succinate dehydrogenase, subunit B (iron-sulfur) (SdhB), succinate dehydrogenase complex subunit B, iron sulfur (Ip) (sdhb), succinate dehydrogenase complex, subunit B, iron sulfur (Ip) (Sdhb), succinate dehydrogenase complex iron sulfur subunit B (Sdhb), succinate dehydrogenase complex, subunit B, iron sulfur (Ip) (sdhb), succinate dehydrogenase complex subunit B, iron sulfur (Ip) S homeolog (sdhb.S), 0710008N11Rik, CG3283, CWS2, Dmel\\CG3283, fj46d06, Ip, IP, PGL4, SDH, SDH-IP, SDH-Ip, SDH1, SDH2, SDHb, sdhB, SDHIP, succinate dehydrogenase 2-3, wu:fj46d06Protein level used designations for SDHB
- succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
- succinate dehydrogenase complex subunit B
- CG3283-PA
- COMPLEX II: iron-sulfur subunit
- SdhB-PA
- iron-sulfur protein subunit of succinate dehydrogenase
- succinate dehydrogenase
- succinate dehydrogenase B
- succinate dehydrogenase Iron-sulfur
- succinate dehydrogenase Iron-sulfur protein
- succinate dehydrogenase iron protein
- succinate dehydrogenase subunit b
- iron-sulfur subunit of complex II
- Iron-sulfur subunit of complex II
- IP
- ip
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