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SDHA Products

(Succinate Dehydrogenase Complex, Subunit A, Flavoprotein (Fp) (SDHA))
This gene encodes a major catalytic subunit of succinate-ubiquinone oxidoreductase, a complex of the mitochondrial respiratory chain. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. Mutations in this gene have been associated with a form of mitochondrial respiratory chain deficiency known as Leigh Syndrome. A pseudogene has been identified on chromosome 3q29. [provided by RefSeq, Jul 2008].

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Featured SDHA Categories

SDHA Antibodies

High quality antibodies with extensive validation data.

SDHA ELISA Kits

Reliable ELISA kits for a wide range of species.

SDHA Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SDHA Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (1)
  • (6)
Cat. No. ABIN3023400
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (7)
Cat. No. ABIN7441595
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IF, IHC (p), ICC
Validations
  • (1)
  • (4)
Cat. No. ABIN2855128
Quantity 100 μL
Datasheet Datasheet

Recommended SDHA ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959731
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5674947
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5674948
Quantity 96 tests
Datasheet Datasheet

Recommended SDHA Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125225
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7505238
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7424752
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our SDHA products

Imai, Inoshita, Meng, Shiba-Fukushima, Hara, Sawamura, Hattori: "Light-driven activation of mitochondrial proton-motive force improves motor behaviors in a Drosophila model of Parkinson's disease." in: Communications biology, Vol. 2, pp. 424, (2020) (PubMed).

Gillen, Brechbuhl, Yamamoto, Kline, Pillai, Hesselberth, Kabos: "Alternative Polyadenylation of PRELID1 Regulates Mitochondrial ROS Signaling and Cancer Outcomes." in: Molecular cancer research : MCR, Vol. 15, Issue 12, pp. 1741-1751, (2018) (PubMed).

Peruzzotti-Jametti, Bernstock, Vicario, Costa, Kwok, Leonardi, Booty, Bicci, Balzarotti, Volpe, Mallucci, Manferrari, Donegà, Iraci, Braga, Hallenbeck, Murphy, Edenhofer, Frezza, Pluchino: "Macrophage-Derived Extracellular Succinate Licenses Neural Stem Cells to Suppress Chronic Neuroinflammation." in: Cell stem cell, Vol. 22, Issue 3, pp. 355-368.e13, (2018) (PubMed).

Schild, Ruhs, Beiter, Zügel, Hudemann, Reimer, Krumholz-Wagner, Wagner, Keller, Eder, Krüger, Krüger, Braun, Nieß, Steinacker, Mooren: "Basal and exercise induced label-free quantitative protein profiling of m. vastus lateralis in trained and untrained individuals." in: Journal of proteomics, Vol. 122, pp. 119-32, (2015) (PubMed).

Yang, Moullan, Auwerx, Gijs: "Fluorescence imaging: super-resolution biological microscopy using virtual imaging by a microsphere nanoscope (small 9/2014)." in: Small (Weinheim an der Bergstrasse, Germany), Vol. 10, Issue 9, pp. 1876, (2014) (PubMed).

Krivitsky, Wang, Wang, Lukyanchuk: "Locomotion of microspheres for super-resolution imaging." in: Scientific reports, Vol. 3, pp. 3501, (2013) (PubMed).

Piantadosi, Suliman: "Transcriptional Regulation of SDHa flavoprotein by nuclear respiratory factor-1 prevents pseudo-hypoxia in aerobic cardiac cells." in: The Journal of biological chemistry, Vol. 283, Issue 16, pp. 10967-77, (2008) (PubMed).

Parfait, Chretien, Rötig, Marsac, Munnich, Rustin: "Compound heterozygous mutations in the flavoprotein gene of the respiratory chain complex II in a patient with Leigh syndrome." in: Human genetics, Vol. 106, Issue 2, pp. 236-43, (2000) (PubMed).

Hirawake, Wang, Kuramochi, Kojima, Kita: "Human complex II (succinate-ubiquinone oxidoreductase): cDNA cloning of the flavoprotein (Fp) subunit of liver mitochondria." in: Journal of biochemistry, Vol. 116, Issue 1, pp. 221-7, (1995) (PubMed).

Morris, Farnsworth, Ackrell, Turnbull, Birch-Machin: "The cDNA sequence of the flavoprotein subunit of human heart succinate dehydrogenase." in: Biochimica et biophysica acta, Vol. 1185, Issue 1, pp. 125-8, (1994) (PubMed).

Synonyms and alternative names related to SDHA

Succinate dehydrogenase, subunit A (flavoprotein) (SdhA), succinate dehydrogenase complex flavoprotein subunit A (SDHA), succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (Sdha), succinate dehydrogenase complex flavoprotein subunit A (Sdha), succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (sdha), succinate dehydrogenase complex subunit A, flavoprotein (Fp) S homeolog (sdha.S), 1500032O14Rik, 2310034D06Rik, 4921513A11, C81073, CG17246, CMD1GG, Dmel\\CG17246, FP, Fp, im:7141001, PGL5, Scs-fp, scs-fp, Sdh, sdh, SDH1, SDH2, Sdha, sdha-b, SDHF, zgc:56051

Protein level used designations for SDHA

  • CG17246-PA
  • CG17246-PB
  • CG17246-PC
  • COMPLEX II: flavoprotein subunit
  • SUCCINYL COENZIME A SYNTHETASE FLAVOPROTEIN SUBUNIT
  • SdhA-PA
  • SdhA-PB
  • SdhA-PC
  • succinate dehydrogenase
  • succinate dehydrogenase A
  • succinate dehydrogenase flavoprotein
  • succinate dehydrogenase flavoprotein subunit
  • succinyl coenzyme A synthetase flavoprotein subunit
  • flavoprotein subunit of complex II
  • succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
  • succinate dehydrogenase complex flavoprotein subunit
  • fp
  • succinate dehydrogenase complex subunit A
  • succinate dehydrogenase flavoprotein subunit A
  • succinate dehydrogenase Fp subunit
  • Flavoprotein subunit of complex II
  • Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
  • mitochondrial succinate dehydrogenase complex subunit A
  • succinate dehydrogenase complex subunit A flavoprotein
  • flavoprotein subunit of complex II B
  • succinate dehydrogenase [ubiquinone] flavoprotein subunit B, mitochondrial
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