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SDCBP Products

(Syndecan Binding Protein (Syntenin) (SDCBP))

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The protein encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

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Featured SDCBP Categories

SDCBP Antibodies

High quality antibodies with extensive validation data.

SDCBP ELISA Kits

Reliable ELISA kits for a wide range of species.

SDCBP Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SDCBP Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF, IP, IHC (p)
Validations
  • (5)
  • (7)
Cat. No. ABIN562830
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (1)
  • (5)
Cat. No. ABIN520095
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7171273
Quantity 100 μg
Datasheet Datasheet

Recommended SDCBP ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970520
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959820
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1160580
Quantity 96 tests
Datasheet Datasheet

Recommended SDCBP Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN667285
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1319349
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1319351
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our SDCBP products

Sun, Sun, Chen, Liao, He, Wang, Chen, Hu, Qiu: "microRNA-27b shuttled by mesenchymal stem cell-derived exosomes prevents sepsis by targeting JMJD3 and downregulating NF-κB signaling pathway." in: Stem cell research & therapy, Vol. 12, Issue 1, pp. 14, (2021) (PubMed).

Sork, Corso, Krjutskov, Johansson, Nordin, Wiklander, Lee, Westholm, Lehtiö, Wood, Mäger, El Andaloussi: "Heterogeneity and interplay of the extracellular vesicle small RNA transcriptome and proteome." in: Scientific reports, Vol. 8, Issue 1, pp. 10813, (2018) (PubMed).

Reithmair, Buschmann, Märte, Kirchner, Hagl, Kaufmann, Pfob, Chouker, Steinlein, Pfaffl, Schelling: "Cellular and extracellular miRNAs are blood-compartment-specific diagnostic targets in sepsis." in: Journal of cellular and molecular medicine, Vol. 21, Issue 10, pp. 2403-2411, (2018) (PubMed).

Kim, Jang, Jeon, Chung, Kim, Kim: "Syntenin increases the invasiveness of small cell lung cancer cells by activating p38, AKT, focal adhesion kinase and SP1." in: Experimental & molecular medicine, Vol. 46, pp. e90, (2014) (PubMed).

Binamé, Sakry, Dimou, Jolivel, Trotter: "NG2 regulates directional migration of oligodendrocyte precursor cells via Rho GTPases and polarity complex proteins." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 26, pp. 10858-74, (2013) (PubMed).

Das, Bhutia, Azab, Kegelman, Peachy, Santhekadur, Dasgupta, Dash, Dent, Grant, Emdad, Pellecchia, Sarkar, Fisher: "MDA-9/syntenin and IGFBP-2 promote angiogenesis in human melanoma." in: Cancer research, Vol. 73, Issue 2, pp. 844-54, (2013) (PubMed).

Raimondo, Morosi, Corbetta, Chinello, Brambilla, Della Mina, Villa, Albo, Battaglia, Bosari, Magni, Pitto: "Differential protein profiling of renal cell carcinoma urinary exosomes." in: Molecular bioSystems, Vol. 9, Issue 6, pp. 1220-33, (2013) (PubMed).

Dasgupta, Menezes, Das, Emdad, Janjic, Bhatia, Mukhopadhyay, Shao, Sarkar, Fisher: "Novel role of MDA-9/syntenin in regulating urothelial cell proliferation by modulating EGFR signaling." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 19, Issue 17, pp. 4621-33, (2013) (PubMed).

Kegelman, Das, Hu, Bacolod, Fuller, Menezes, Emdad, Dasgupta, Baldwin, Bruce, Dent, Pellecchia, Sarkar, Fisher: "MDA-9/syntenin is a key regulator of glioma pathogenesis." in: Neuro-oncology, Vol. 16, Issue 1, pp. 50-61, (2013) (PubMed).

Das, Bhutia, Sokhi, Azab, Su, Boukerche, Anwar, Moen, Chatterjee, Pellecchia, Sarkar, Fisher: "Raf kinase inhibitor RKIP inhibits MDA-9/syntenin-mediated metastasis in melanoma." in: Cancer research, Vol. 72, Issue 23, pp. 6217-26, (2012) (PubMed).

Synonyms and alternative names related to SDCBP

syndecan binding protein (SDCBP), syndecan binding protein (Sdcbp), syndecan binding protein L homeolog (sdcbp.L), syndecan binding protein (LOC732879), syndecan binding protein (syntenin) 2 (sdcbp2), syndecan binding protein (syntenin) (sdcbp), MDA-9, mda-9, MGC81274, sb:eu862, si:dkey-235k4.1, ST1, st1, SYCL, Sycl, sycl, syntenin, syntenin-1, TACIP18, tacip18, wu:fc51c03, wu:fk31e01, zgc:55679, zgc:77716

Protein level used designations for SDCBP

  • melanoma differentiation associated protein-9
  • melanoma differentiation-associated protein 9
  • pro-TGF-alpha cytoplasmic domain-interacting protein 18
  • scaffold protein Pbp1
  • syndecan-binding protein 1
  • syntenin-1
  • syndecan interacting protein
  • syntenin
  • syndecan binding protein
  • syntenin-b
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