SCO2 Products
(SCO2 Cytochrome C Oxidase Assembly Protein (SCO2))
Categories
Cytochrome c oxidase (COX) catalyzes the transfer of electrons from cytochrome c to molecular oxygen, which helps to maintain the proton gradient across the inner mitochondrial membrane that is necessary for aerobic ATP production. Human COX is a multimeric protein complex that requires several assembly factors\; this gene encodes one of the COX asembly factors. The encoded protein is a metallochaperone that is involved in the biogenesis of cytochrome c oxidase subunit II. Mutations in this gene are associated with fatal infantile encephalocardiomyopathy. [provided by RefSeq, Dec 2009].
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Featured SCO2 Categories
SCO2 Antibodies
High quality antibodies with extensive validation data.
SCO2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SCO2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (5)
Cat. No.
ABIN6147457
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC
Validations
- (3)
Cat. No.
ABIN7263007
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
IHC, ELISA
Validations
- (2)
Cat. No.
ABIN7166101
Quantity
100 μL
Datasheet
Datasheet
Recommended SCO2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6234939
Quantity
96 tests
Datasheet
Datasheet
Recommended SCO2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1319298
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1319300
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7505240
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our SCO2 products
: "COA6 Is Structurally Tuned to Function as a Thiol-Disulfide Oxidoreductase in Copper Delivery to Mitochondrial Cytochrome c Oxidase." in: Cell reports, Vol. 29, Issue 12, pp. 4114-4126.e5, (2020) (PubMed).: "SCO2 induces p53-mediated apoptosis by Thr845 phosphorylation of ASK-1 and dissociation of the ASK-1-Trx complex." in: Molecular and cellular biology, Vol. 33, Issue 7, pp. 1285-302, (2013) (PubMed).
: "p53 regulates mitochondrial respiration." in: Science (New York, N.Y.), Vol. 312, Issue 5780, pp. 1650-3, (2006) (PubMed).
: "Human Sco1 and Sco2 function as copper-binding proteins." in: The Journal of biological chemistry, Vol. 280, Issue 40, pp. 34113-22, (2005) (PubMed).
: "Fatal infantile cardioencephalomyopathy with COX deficiency and mutations in SCO2, a COX assembly gene." in: Nature genetics, Vol. 23, Issue 3, pp. 333-7, (1999) (PubMed).
: "SCO1 and SCO2 act as high copy suppressors of a mitochondrial copper recruitment defect in Saccharomyces cerevisiae." in: The Journal of biological chemistry, Vol. 271, Issue 34, pp. 20531-5, (1996) (PubMed).
Synonyms and alternative names related to SCO2
SCO cytochrome oxidase deficient homolog 2 (yeast) (SCO2), SCO2 cytochrome c oxidase assembly protein (Sco2), SCO2, cytochrome c oxidase assembly protein (SCO2), CEMCOX1, MYP6, SCO1LProtein level used designations for SCO2
- protein SCO2 homolog, mitochondrial
- SCO cytochrome oxidase deficient homolog 2
- cytochrome oxidase deficient homolog 2
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