SCNN1A Products
(Sodium Channel, Nonvoltage-Gated 1 alpha (SCNN1A))
Categories
Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the alpha subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), a rare salt wasting disease resulting from target organ unresponsiveness to mineralocorticoids. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2009].
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Featured SCNN1A Categories
SCNN1A Antibodies
High quality antibodies with extensive validation data.
SCNN1A ELISA Kits
Reliable ELISA kits for a wide range of species.
SCNN1A Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SCNN1A Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Application
WB, IHC, IF, IP, ICC
Validations
- (19)
- (5)
Cat. No.
ABIN863203
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC, IF, ICC
Validations
- (19)
- (5)
Cat. No.
ABIN863204
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC, IF, IP, ICC
Validations
- (19)
- (4)
Cat. No.
ABIN863202
Quantity
100 μg
Datasheet
Datasheet
Recommended SCNN1A ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959542
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959543
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5651663
Quantity
96 tests
Datasheet
Datasheet
Recommended SCNN1A Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7407787
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7397414
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7417705
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our SCNN1A products
: "Mambalgin-2 Inhibits Lung Adenocarcinoma Growth and Migration by Selective Interaction With ASIC1/α-ENaC/γ-ENaC Heterotrimer." in: Frontiers in oncology, Vol. 12, pp. 904742, (2022) (PubMed).: "Mambalgin-2 Inhibits Growth, Migration, and Invasion of Metastatic Melanoma Cells by Targeting the Channels Containing an ASIC1a Subunit Whose Up-Regulation Correlates with Poor Survival Prognosis." in: Biomedicines, Vol. 9, Issue 10, (2021) (PubMed).
: "Increased ENaC activity during kidney preservation in Wisconsin solution." in: BMC nephrology, Vol. 20, Issue 1, pp. 145, (2020) (PubMed).
: "The E3 ubiquitin ligase Siah1 regulates adrenal gland organization and aldosterone secretion." in: JCI insight, Vol. 2, Issue 23, (2019) (PubMed).
: "Postprandial Effects on ENaC-Mediated Sodium Absorption." in: Scientific reports, Vol. 9, Issue 1, pp. 4296, (2019) (PubMed).
: "Single-walled carbon nanohorn aggregates promotes mitochondrial dysfunction-induced apoptosis in hepatoblastoma cells by targeting SIRT3." in: International journal of oncology, Vol. 53, Issue 3, pp. 1129-1137, (2018) (PubMed).
: "Oxidized low-density lipoprotein stimulates epithelial sodium channels in endothelial cells of mouse thoracic aorta." in: British journal of pharmacology, Vol. 175, Issue 8, pp. 1318-1328, (2018) (PubMed).
: "Epithelial Sodium Channel-α Mediates the Protective Effect of the TNF-Derived TIP Peptide in Pneumolysin-Induced Endothelial Barrier Dysfunction." in: Frontiers in immunology, Vol. 8, pp. 842, (2017) (PubMed).
: "Renal sodium transport in renin-deficient Dahl salt-sensitive rats." in: Journal of the renin-angiotensin-aldosterone system : JRAAS, Vol. 17, Issue 3, (2017) (PubMed).
: "Mineralocorticoid receptor stimulation induces urinary storage dysfunction via upregulation of epithelial sodium channel expression in the rat urinary bladder epithelium." in: Journal of pharmacological sciences, Vol. 130, Issue 4, pp. 219-25, (2016) (PubMed).
Synonyms and alternative names related to SCNN1A
sodium channel epithelial 1 alpha subunit (Scnn1a), sodium channel epithelial 1 alpha subunit (SCNN1A), sodium channel, nonvoltage-gated 1 alpha (Scnn1a), sodium channel, non voltage gated 1 alpha subunit L homeolog (scnn1a.L), alphaxENaC, BESC2, besc2, ENaC, ENAC, ENaCa, enaca, ENaCalpha, mENaC, SCNEA, SCNN1, Scnn1, scnn1, SCNN1AProtein level used designations for SCNN1A
- SCNEA
- alpha-ENaC
- alpha-NaCH
- amiloride-sensitive sodium channel subunit alpha
- epithelial Na(+) channel subunit alpha
- epithelial sodium channel alpha subunit
- nonvoltage-gated sodium channel 1 subunit alpha
- sodium channel, nonvoltage-gated, type I, alpha
- alpha ENaC-2
- amiloride-sensitive epithelial sodium channel alpha subunit
- amiloride-sensitive sodium channel subunit alpha 2
- nasal epithelial sodium channel alpha subunit
- sodium channel, nonvoltage-gated 1 alpha
- ENaC alpha
- amiloride-sensitive epithelial sodium channel
- sodium channel, nonvoltage-gated, type I, alpha polypeptide
- alpha ENaC
- epithelial sodium channel ENaC alpha subunit
- alpha cENaC 431
- amiloride-sensitve epithelial sodium channel alpha subunit
- alpha-subunit renal epithelial sodium channel
- epithelium sodium channel alpha subunit
- sodium channel, nonvoltage-gated 1, alpha
- amiloride-sensitive sodium channel alpha subunit
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