SCN7A Products
(Sodium Channel, Voltage-Gated, Type VII, alpha Subunit (SCN7A))
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This gene encodes one of the many voltage-gated sodium channel proteins. For proper functioning of neurons and muscles during action potentials, voltage-gated sodium channels direct sodium ion diffusion for membrane depolarization. This sodium channel protein has some atypical characteristics\; the similarity between the human and mouse proteins is lower compared to other orthologous sodium channel pairs. Also, the S4 segments, which sense voltage changes, have fewer positive charged residues that in other sodium channels\; domain 4 has fewer arginine and lysine residues compared to other sodium channel proteins. Several alternatively spliced transcript variants exist, but the full-length natures of all of them remain unknown. [provided by RefSeq, Dec 2011].
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SCN7A Antibodies
High quality antibodies with extensive validation data.
Recommended SCN7A Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, WB, IHC
Validations
- (3)
Cat. No.
ABIN7169925
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IF
Validations
- (1)
Cat. No.
ABIN7184122
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
ELISA, IF (cc), IF (p), ICC, IHC (fro), IHC (p)
Validations
- (1)
Cat. No.
ABIN1386696
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our SCN7A products
: "Induction of sodium channel Na(x) (SCN7A) expression in rat and human hippocampus in temporal lobe epilepsy." in: Epilepsia, Vol. 51, Issue 9, pp. 1791-800, (2010) (PubMed).Synonyms and alternative names related to SCN7A
sodium channel, voltage-gated, type VII, alpha (Scn7a), sodium voltage-gated channel alpha subunit 7 (Scn7a), sodium voltage-gated channel alpha subunit 7 (SCN7A), 1110034K09Rik, AI642000, Na-G, NaG, Nav2, Nav2.1, Nav2.2, Nav2.3, Nax, Scn6a, SCN6AProtein level used designations for SCN7A
- sodium channel, voltage-gated, type VI, alpha polypeptide
- sodium channel, voltage-gated, type VII, alpha polypeptide
- sodium channel protein type 7 subunit alpha
- sodium channel voltage-gated type VI alpha polypeptide
- sodium channel, voltage-gated, type 6, alpha polypeptide
- putative voltage-gated sodium channel subunit alpha Nax
- sodium channel protein cardiac and skeletal muscle subunit alpha
- sodium channel protein type VII subunit alpha
- voltage-dependent sodium channel alpha subunit
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