SCN1B Products
(Sodium Channel, Voltage-Gated, Type I, beta (SCN1B))
Categories
Voltage-gated sodium channels are heteromeric proteins that function in the generation and propagation of action potentials in muscle and neuronal cells. They are composed of one alpha and two beta subunits, where the alpha subunit provides channel activity and the beta-1 subunit modulates the kinetics of channel inactivation. This gene encodes a sodium channel beta-1 subunit. Mutations in this gene result in generalized epilepsy with febrile seizures plus, Brugada syndrome 5, and defects in cardiac conduction. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009].
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Featured SCN1B Categories
SCN1B Antibodies
High quality antibodies with extensive validation data.
SCN1B Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SCN1B Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
WB, FACS, IHC (p)
Validations
- (3)
Cat. No.
ABIN654602
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (2)
Cat. No.
ABIN7169933
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, FACS, IHC (p), EIA
Validations
- (3)
Cat. No.
ABIN954692
Quantity
0.4 mL
Datasheet
Datasheet
Recommended SCN1B Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1319273
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our SCN1B products
: "Antisense-mediated post-transcriptional silencing of SCN1B gene modulates sodium channel functional expression." in: Biology of the cell / under the auspices of the European Cell Biology Organization, Vol. 106, Issue 1, pp. 13-29, (2014) (PubMed).: "Identification of an intra-molecular disulfide bond in the sodium channel ?1-subunit." in: Biochemical and biophysical research communications, Vol. 420, Issue 2, pp. 364-7, (2012) (PubMed).
: "Mice lacking sodium channel beta1 subunits display defects in neuronal excitability, sodium channel expression, and nodal architecture." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 24, Issue 16, pp. 4030-42, (2004) (PubMed).
Synonyms and alternative names related to SCN1B
sodium channel, voltage-gated, type I, beta (Scn1b), sodium voltage-gated channel beta subunit 1 (Scn1b), sodium voltage-gated channel beta subunit 1 (SCN1B), GEFSP1Protein level used designations for SCN1B
- sodium channel subunit beta-1
- sodium channel, voltage-gated, type I, beta polypeptide
- sodium channel voltage-gated type 1 beta polypeptide
- sodium channel voltage-gated type I beta polypeptide
- sodium channel, voltage-gated, type 1, beta polypeptide
- sodium channel beta-1 subunit
- sodium channel beta 1-subunit
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