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SAT1 Products

(Spermidine/spermine N1-Acetyltransferase 1 (SAT1))
The protein encoded by this gene belongs to the acetyltransferase family, and is a rate-limiting enzyme in the catabolic pathway of polyamine metabolism. It catalyzes the acetylation of spermidine and spermine, and is involved in the regulation of the intracellular concentration of polyamines and their transport out of cells. Defects in this gene are associated with keratosis follicularis spinulosa decalvans (KFSD). Alternatively spliced transcripts have been found for this gene.[provided by RefSeq, Sep 2009].

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Featured SAT1 Categories

SAT1 Antibodies

High quality antibodies with extensive validation data.

SAT1 ELISA Kits

Reliable ELISA kits for a wide range of species.

SAT1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SAT1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (5)
Cat. No. ABIN1327663
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application IHC, WB, IP, ICC
Validations
  • (2)
Cat. No. ABIN7441391
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, WB, ELISA
Validations
  • (2)
Cat. No. ABIN7149862
Quantity 100 μg
Datasheet Datasheet

Recommended SAT1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970391
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959665
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959666
Quantity 96 tests
Datasheet Datasheet

Recommended SAT1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1319174
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1319172
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (3)
  • (1)
Cat. No. ABIN1095568
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our SAT1 products

Lane, Bae, Siafakas, Suryo Rahmanto, Al-Akra, Jansson, Casero, Richardson: "Coupling of the polyamine and iron metabolism pathways in the regulation of proliferation: Mechanistic links to alterations in key polyamine biosynthetic and catabolic enzymes." in: Biochimica et biophysica acta. Molecular basis of disease, Vol. 1864, Issue 9 Pt B, pp. 2793-2813, (2018) (PubMed).

Liao, Lasbury, Wang, Zhang, Durant, Murakami, Matsufuji, Lee: "Pneumocystis mediates overexpression of antizyme inhibitor resulting in increased polyamine levels and apoptosis in alveolar macrophages." in: The Journal of biological chemistry, Vol. 284, Issue 12, pp. 8174-84, (2009) (PubMed).

Sun, Liu, Yang, Xu, Yan, Wang, Liu: "Adenovirus-mediated expression of SSAT inhibits colorectal cancer cell growth in vitro." in: Acta pharmacologica Sinica, Vol. 29, Issue 5, pp. 606-13, (2008) (PubMed).

Xiao, Celano, Mank, Griffin, Jabs, Hawkins, Casero: "Structure of the human spermidine/spermine N1-acetyltransferase gene (exon/intron gene organization and localization to Xp22.1)." in: Biochemical and biophysical research communications, Vol. 187, Issue 3, pp. 1493-502, (1992) (PubMed).

Casero, Celano, Ervin, Applegren, Wiest, Pegg: "Isolation and characterization of a cDNA clone that codes for human spermidine/spermine N1-acetyltransferase." in: The Journal of biological chemistry, Vol. 266, Issue 2, pp. 810-4, (1991) (PubMed).

Xiao, Celano, Mank, Pegg, Casero: "Characterization of a full-length cDNA which codes for the human spermidine/spermine N1-acetyltransferase." in: Biochemical and biophysical research communications, Vol. 179, Issue 1, pp. 407-15, (1991) (PubMed).

Synonyms and alternative names related to SAT1

spermidine/spermine N1-acetyltransferase 1 (SAT1), spermidine/spermine N1-acetyltransferase 1 L homeolog (sat1.L), spermidine/spermine N1-acetyltransferase 1 (sat1), spermidine/spermine N1-acetyl transferase 1 (Sat1), spermidine/spermine N1-acetyltransferase 1 (Sat1), spermidine/spermine N1-acetyltransferase 1b (sat1b), AA617398, Ab2-402, DC21, dc21, KFSD, kfsd, KFSDX, kfsdx, SAT, sat, Sat, sat1, SAT1, sat1b, si:rp71-1f1.2, SSAT, ssat, SSAT-1, ssat-1

Protein level used designations for SAT1

  • diamine N-acetyltransferase 1
  • diamine acetyltransferase 1
  • polyamine N-acetyltransferase 1
  • putrescine acetyltransferase
  • spermidine/spermine N(1)-acetyltransferase 1
  • spermidine/spermine N1-acetyltransferase alpha
  • SSAT
  • SSAT-1
  • spermidine/spermine N-acetyltransferase
  • diamine N-acetyltransferase 1 b
  • spermidine/spermine N1-acetyltransferase 1 b
  • spermidine/spermine N1-acetyltransferase 1
  • Spermidine / spermine N1-acyltransferase (diamine acetyltransferase)
  • Polyamine N-acetyltransferase 1
  • Putrescine acetyltransferase
  • Spermidine/spermine N(1)-acetyltransferase 1
  • spermidine/spermine N1-acetyl transferase 1
  • spermidine/spermine N1-acetyl transferase 1b
  • ssat1a
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