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SARS2 Products

(seryl-tRNA Synthetase 2, Mitochondrial (SARS2))

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This gene encodes the mitochondrial seryl-tRNA synthethase precursor, a member of the class II tRNA synthetase family. The mature enzyme catalyzes the ligation of Serine to tRNA(Ser) and participates in the biosynthesis of selenocysteinyl-tRNA(sec) in mitochondria. The enzyme contains an N-terminal tRNA binding domain and a core catalytic domain. It functions in a homodimeric form, which is stabilized by tRNA binding. This gene is regulated by a bidirectional promoter that also controls the expression of mitochondrial ribosomal protein S12. Both genes are within the critical interval for the autosomal dominant deafness locus DFNA4 and might be linked to this disease. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Mar 2009].

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Featured SARS2 Categories

SARS2 Antibodies

High quality antibodies with extensive validation data.

SARS2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SARS2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB
Validations
  • (3)
Cat. No. ABIN527263
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
Cat. No. ABIN392300
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
Cat. No. ABIN392301
Quantity 400 μL
Datasheet Datasheet

Recommended SARS2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6233637
Quantity 96 tests
Datasheet Datasheet

Recommended SARS2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1319160
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7423477
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7422997
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our SARS2 products

Müller, Deschauer, Neudecker, Zierz: "Late-onset mitochondrial myopathy with dystrophic changes due to a G7497A mutation in the mitochondrial tRNA(Ser(UCN)) gene." in: Acta neuropathologica, Vol. 110, Issue 4, pp. 426-30, (2005) (PubMed).

Gibbons, Yan, Li, Li, Guan: "Genomic organization, expression, and subcellular localization of mouse mitochondrial seryl-tRNA synthetase." in: Biochemical and biophysical research communications, Vol. 317, Issue 3, pp. 774-8, (2004) (PubMed).

Yokogawa, Shimada, Takeuchi, Benkowski, Suzuki, Omori, Ueda, Nishikawa, Spremulli, Watanabe: "Characterization and tRNA recognition of mammalian mitochondrial seryl-tRNA synthetase." in: The Journal of biological chemistry, Vol. 275, Issue 26, pp. 19913-20, (2000) (PubMed).

Synonyms and alternative names related to SARS2

seryl-aminoacyl-tRNA synthetase 2 (Sars2), seryl-tRNA synthetase 2, mitochondrial (SARS2), seryl-tRNA synthetase 2, mitochondrial (Sars2), 2410015F05Rik, D7Ertd353e, mtSerRS, SARS, SARSM, SerRS, SerRSmt, SERS, SYS

Protein level used designations for SARS2

  • serine--tRNA ligase, mitochondrial
  • seryl-tRNA synthetase, mitochondrial
  • seryl-tRNA(Ser/Sec) synthetase
  • mitochondrial seryl-tRNA synthetase
  • serine tRNA ligase 2, mitochondrial
  • serine-tRNA ligase, mitochondrial
  • seryl-aminoacyl-tRNA synthetase 2
  • serRSmt
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